OR11H7: A GPCR Targeted for Drug Development (G390441)
OR11H7: A GPCR Targeted for Drug Development
Olfactory receptor, family 11, subfamily H, member 7 (OR11H7) is a protein that plays a crucial role in human sensory function. OR11H7 is a G protein-coupled receptor (GPCR), which means it is a transmembrane protein that is involved in cell-cell signaling. OR11H7 is expressed in various tissues of the body, including the brain, eye, and respiratory tract. It is involved in the sense of smell, as well as the regulation of pain and inflammation.
OR11H7 has been identified as a potential drug target due to its involvement in several neuropsychiatric and neurological disorders. Its function in sensory processing and neurotransmission makes it an attractive target for the development of new treatments for conditions such as Alzheimer's disease, Parkinson's disease, and chronic pain.
OR11H7 has been shown to play a role in the development and progression of several neurological disorders, including Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and the development of neurodegeneration. OR11H7 has been shown to be involved in the regulation of neurotransmitter release from neurons, which is critical for the function of the brain.
In addition to its involvement in neurological disorders, OR11H7 has also been shown to be involved in the regulation of pain. Chronic pain is a common condition that is associated with significant morbidity and quality of life. OR11H7 has been shown to play a role in the regulation of pain signaling, as well as the modulation of pain perception.
OR11H7 has also been shown to be involved in the regulation of inflammation. Inflammation is a fundamental biological response to tissue damage and infection, and it is involved in the development and progression of many diseases. OR11H7 has been shown to play a role in the regulation of inflammatory responses, as well as the modulation of immune cell function.
Due to its involvement in several neuropsychiatric and neurological disorders, OR11H7 has been identified as a potential drug target. Several small molecules have been shown to interact with OR11H7, and studies have demonstrated the potential efficacy of these compounds in the treatment of conditions such as Alzheimer's disease, Parkinson's disease, and chronic pain. However, more research is needed to fully understand the function of OR11H7 and its potential as a drug target.
In conclusion, OR11H7 is a GPCR that is involved in the sense of smell, the regulation of pain, and the regulation of inflammation. Its function in sensory processing and neurotransmission makes it an attractive target for the development of new treatments for conditions such as Alzheimer's disease, Parkinson's disease, and chronic pain. Further research is needed to fully understand the function of OR11H7 as a drug target and to develop effective treatments for these conditions.
Protein Name: Olfactory Receptor Family 11 Subfamily H Member 7 (gene/pseudogene)
Functions: Odorant receptor. Activated by isovaleric acid
More Common Targets
OR11J2P | OR11J5P | OR11K2P | OR11L1 | OR11M1P | OR12D2 | OR12D3 | OR13A1 | OR13C2 | OR13C3 | OR13C4 | OR13C5 | OR13C8 | OR13C9 | OR13D1 | OR13F1 | OR13G1 | OR13H1 | OR13J1 | OR13Z2P | OR14A16 | OR14A2 | OR14C36 | OR14I1 | OR14J1 | OR14L1P | OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2