Target Name: OR14L1P
NCBI ID: G127617
Other Name(s): Olfactory receptor | putative olfactory receptor 5AV1 | Olfactory receptor family 14 subfamily L member 1 pseudogene | OR1-35 | olfactory receptor OR1-36 | Olfactory receptor, family 5, subfamily AV, member 1 pseudogene | OR14L1 | olfactory receptor, family 5, subfamily AV, member 1 pseudogene | OR1-36 | OR5AV1 | Putative olfactory receptor 5AV1 | olfactory receptor family 14 subfamily L member 1 pseudogene | olfactory receptor OR1-35 pseudogene | Olfactory receptor OR1-35 pseudogene | Olfactory receptor OR1-36 | OR5AV1P

OR14L1P: A Potential Drug Target and Biomarker for Neurological Disorders

Olfactory receptor (OR) 14L1P is a protein that is expressed in the human nasal cavity and is responsible for mediating the sense of smell. OR14L1P has been identified as a potential drug target and a biomarker for various neurological and psychiatric disorders.

The sense of smell is an essential aspect of human life that plays a critical role in our ability to identify and consume food, recognize friends and loved ones, and navigate our environment. The olfactory system is composed of the sense organs, including the nose and the brain, which work together to detect and interpret the sensory information that enters the body.

OR14L1P is a transmembrane protein that is expressed in the nasal cavity and is involved in the function of the olfactory system. It is a member of the superfamily of G protein-coupled receptors (GPCRs), which are a family of transmembrane proteins that play a critical role in cellular signaling. GPCRs are characterized by the presence of a transmembrane domain, a catalytic domain, and a carpal tunnel region.

OR14L1P is involved in the detection and perception of odor, which is the ability to identify and identify the source, pattern, and intensity of a particular smell. OR14L1P is a critical protein in the olfactory system, as it helps to regulate the flow of sensory information from the sensory neurons to the brain.

OR14L1P is a potential drug target because of its involvement in the function of the olfactory system. Activation of OR14L1P has been shown to induce the release of sensory information from the neurons, leading to the sensation of smell. Additionally, blockade of OR14L1P has been shown to reverse the effects of sensory deprivation, suggesting that it may play a role in the treatment of disorders that are characterized by sensory dysfunction, such as Alzheimer's disease, Parkinson's disease, and chronic insomnia.

OR14L1P is also potential biomarker for various neurological and psychiatric disorders. For example, reduced expression of OR14L1P has been observed in the brains of individuals with Alzheimer's disease, which is a leading cause of dementia. Additionally, altered levels of OR14L1P have been observed in the brains of individuals with depression and anxiety, suggesting that it may play a role in the pathophysiology of these disorders.

In addition to its potential clinical applications, OR14L1P also has potential as a research tool for the study of olfactory function and the underlying mechanisms of sensory processing. OR14L1P can be overexpressed in a variety of cell types, including primary cultures of neurons and glial cells, allowing researchers to study its role in the development, maintenance, and regulation of olfactory function. Additionally, the use of RNA interference technology has allowed researchers to knockdown the expression of OR14L1P and to study its role in the regulation of olfactory sensitivity.

In conclusion, OR14L1P is a protein that is involved in the function of the olfactory system and has the potential to be a drug target and a biomarker for various neurological and psychiatric disorders. Further research is needed to fully understand the role of OR14L1P in sensory processing and the underlying mechanisms of its function.

Protein Name: Olfactory Receptor Family 14 Subfamily L Member 1 Pseudogene

Functions: Odorant receptor

More Common Targets

OR1A1 | OR1A2 | OR1B1 | OR1C1 | OR1D2 | OR1D4 | OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6