OR1D4: A Unique Protein with Potential Drug Targeting and Biomarker Properties

OR1D4: A Unique Protein with Potential Drug Targeting and Biomarker Properties

OR1D4 (OR17-30) is a protein that is expressed in various tissues of the body, including the brain, pancreas, and heart. It is a member of the OR1 family of transmembrane proteins, which are characterized by the presence of a short cytoplasmic tail and a unique topology of the transmembrane region. OR1D4 is unique among its family members due to the presence of a unique N-terminal region that contains a conserved nucleotide and a putative transmembrane domain.

The OR1D4 protein is of interest as a potential drug target due to its involvement in several cellular processes that are important for human health. One of the most significant functions of OR1D4 is its role in the regulation of cellular signaling pathways. OR1D4 has been shown to play a critical role in the regulation of the insulin/IGF-1 signaling pathway, which is involved in the regulation of glucose metabolism and energy homeostasis.

In addition to its role in cellular signaling, OR1D4 is also of interest as a potential biomarker for several diseases. For example, OR1D4 has been shown to be decreased in individuals with type 2 diabetes, which is a major risk factor for cardiovascular disease. This suggests that OR1D4 may be a useful biomarker for diagnosing and monitoring diabetes, as well as for identifying individuals at risk for cardiovascular disease.

Another potential application of OR1D4 is its potential as a therapeutic target for treating neurodegenerative diseases. OR1D4 has been shown to be involved in the regulation of several neurotransmitter systems, including the regulation of dopamine release. This suggests that OR1D4 may be a useful target for treating neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.

In conclusion, OR1D4 is a unique and highly conserved protein that plays a critical role in several cellular processes that are important for human health. Its potential as a drug target and biomarker make it an attractive target for further research and development. Further studies are needed to fully understand the functions of OR1D4 and its potential as a therapeutic agent.

Protein Name: Olfactory Receptor Family 1 Subfamily D Member 4

Functions: Odorant receptor

More Common Targets

OR1D5 | OR1E1 | OR1E2 | OR1E3 | OR1F1 | OR1F2P | OR1G1 | OR1I1 | OR1J1 | OR1J2 | OR1J4 | OR1K1 | OR1L1 | OR1L3 | OR1L4 | OR1L6 | OR1L8 | OR1M1 | OR1N1 | OR1N2 | OR1P1 | OR1Q1 | OR1S1 | OR1S2 | OR2A1 | OR2A1-AS1 | OR2A12 | OR2A14 | OR2A2 | OR2A20P | OR2A25 | OR2A4 | OR2A42 | OR2A7 | OR2A9P | OR2AE1 | OR2AG1 | OR2AG2 | OR2AJ1 | OR2AK2 | OR2AL1P | OR2AM1P | OR2AP1 | OR2AT4 | OR2B11 | OR2B2 | OR2B3 | OR2B6 | OR2C1 | OR2C3 | OR2D2 | OR2D3 | OR2F1 | OR2F2 | OR2G2 | OR2G3 | OR2G6 | OR2H1 | OR2H2 | OR2I1P | OR2J1 | OR2J2 | OR2J3 | OR2J4P | OR2K2 | OR2L13 | OR2L1P | OR2L2 | OR2L3 | OR2L5 | OR2L8 | OR2L9P | OR2M1P | OR2M2 | OR2M3 | OR2M4 | OR2M5 | OR2M7 | OR2Q1P | OR2S2 | OR2T1 | OR2T10 | OR2T11 | OR2T12 | OR2T2 | OR2T27 | OR2T29 | OR2T3 | OR2T33 | OR2T34 | OR2T35 | OR2T4 | OR2T5 | OR2T6 | OR2T7 | OR2T8 | OR2U1P | OR2V1 | OR2V2 | OR2W1