Understanding CTBP1: Potential Drug Target Or Biomarker (G1487)

Target Name: CTBP1

NCBI ID: G1487

Understanding CTBP1: Potential Drug Target Or Biomarker

CTBP1, also known as C-terminal binding protein 1, is a protein that is expressed in various tissues throughout the body, including the brain, heart, kidneys, and liver. It is a member of the CTBP family, which is a group of transmembrane proteins that are characterized by their ability to interact with various signaling molecules, including cytokines and transcription factors.

The most well-studied member of the CTBP family is CTBP2, which is a protein that is expressed in the brain and is known to play a role in the regulation of neurotransmitter release and synaptic plasticity. However, there is also some evidence to suggest that CTBP1 may have similar functions in certain tissues.

One of the key functions of CTBP1 is its ability to interact with cytokines, which are proteins that are released by the immune system in response to the presence of foreign substances or invading cells. CTBP1 has been shown to play a role in the regulation of the cytokine signal transduction pathway, which is a complex series of events that are involved in the regulation of immune responses and inflammation.

In addition to its role in cytokine signaling, CTBP1 is also involved in the regulation of cellular signaling pathways that are important for the development and maintenance of tissues and organs. For example, studies have suggested that CTBP1 may be involved in the regulation of cell proliferation, migration, and adhesion, as well as in the regulation of cell death.

The potential utility of CTBP1 as a drug target or biomarker comes from its ability to interact with a wide range of signaling molecules, including cytokines, transcription factors, and cell surface proteins. This suggests that CTBP1 may be a useful target for the development of new therapies for a variety of diseases, including neurodegenerative disorders, cancer, and cardiovascular disease.

In addition to its potential therapeutic applications, CTBP1 is also of interest as a biomarker for certain diseases. For example, some studies have suggested that changes in the expression of CTBP1 may be associated with the development of certain diseases, such as neurodegenerative disorders. Additionally, the ability of CTBP1 to interact with cytokines and other signaling molecules may make it a useful biomarker for certain types of cancer, such as melanoma and breast cancer.

Overall, CTBP1 is a protein that is expressed in a variety of tissues and is involved in a wide range of cellular signaling pathways. Its ability to interact with a variety of signaling molecules makes it a potential target for the development of new therapies for a variety of diseases. Further research is needed to fully understand the functions of CTBP1 and its potential as a drug or biomarker.

Protein Name: C-terminal Binding Protein 1

Functions: Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation

More Common Targets