CTNND1: A Promising Drug Target for Neurological Disorders (G1500)
CTNND1: A Promising Drug Target for Neurological Disorders
CTNND1, short for cluster keratin neuron 1, is a protein that is expressed in the nervous system and has been identified as a potential drug target in the treatment of various neurological disorders. The protein is known for its role in the development and maintenance of synapses, which are the structural elements that allow communication between neurons.
Synapses are a vital part of the nervous system, as they allow the exchange of information between neurons and the transmission of signals from the brain to the rest of the body. CTNND1 is involved in the formation and maintenance of synapses, which is essential for the proper functioning of the nervous system.
One of the most promising aspects of CTNND1 is its potential as a drug target. Studies have shown that blocking the activity of CTNND1 can lead to the improvement of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.
In addition to its potential as a drug target, CTNND1 has also been identified as a potential biomarker for various neurological disorders. The protein is often used as a marker for the diagnosis of neurodegenerative disorders, as its levels are often reduced in these conditions. This protein is often used as a marker for the diagnosis of neurodegenerative disorders, as its levels are often reduced in these conditions. makes CTNND1 an attractive target for researchers to study as a potential diagnostic or therapeutic target.
The research on CTNND1 is still in its early stages, but it is clear that this protein has the potential to be a valuable tool for the treatment of neurological disorders. As research continues, scientists and doctors will continue to explore the potential uses of CTNND1 and its potential as a drug target.
Protein Name: Catenin Delta 1
Functions: Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability (PubMed:14610055, PubMed:20371349). Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics (PubMed:10207085, PubMed:20371349). Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors (PubMed:17344476)
More Common Targets
CTNND2 | CTNS | CTPS1 | CTPS2 | CTR9 | CTRB1 | CTRB2 | CTRC | CTRL | CTSA | CTSB | CTSC | CTSD | CTSE | CTSF | CTSG | CTSH | CTSK | CTSL | CTSL3P | CTSLP2 | CTSLP3 | CTSLP6 | CTSLP8 | CTSO | CTSS | CTSV | CTSW | CTSZ | CTTN | CTTNBP2 | CTTNBP2NL | CTU1 | CTU2 | CTXN1 | CTXN2 | CTXN3 | CTXND1 | CTXND2 | CUBN | CUBNP2 | CUEDC1 | CUEDC2 | CUL1 | CUL2 | CUL3 | CUL4A | CUL4B | CUL5 | CUL7 | CUL9 | Cullin | CUTA | CUTALP | CUTC | CUX1 | CUX2 | CUZD1 | CWC15 | CWC22 | CWC25 | CWC27 | CWF19L1 | CWF19L2 | CWH43 | CX3CL1 | CX3CR1 | CXADR | CXADRP1 | CXADRP2 | CXADRP3 | CXCL1 | CXCL10 | CXCL11 | CXCL12 | CXCL13 | CXCL14 | CXCL16 | CXCL17 | CXCL2 | CXCL3 | CXCL5 | CXCL6 | CXCL8 | CXCL9 | CXCR1 | CXCR2 | CXCR2P1 | CXCR3 | CXCR4 | CXCR5 | CXCR6 | CXorf30 | CXorf38 | CXorf49 | CXorf49B | CXorf51A | CXorf51B | CXorf58 | CXorf65