Target Name: EN1
NCBI ID: G2019
Other Name(s): engrailed homolog 1 | Engrailed homolog 1 | Hu-En-1 | Homeobox protein en-1 | homeobox protein en-1 | ENDOVESLB | HME1_HUMAN | Homeobox protein engrailed-1 | engrailed homeobox 1 | Engrailed homeobox 1 | hu-En-1

EN1: Potential Drug Target for Cancer and Other Diseases

EN1, or engrailed homolog 1, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer.

One of the key functions of EN1 is its role in cell proliferation. EN1 has been shown to promote the growth and survival of cancer cells, and to inhibit the death of cancer cells. This suggests that EN1 may be a potential drug target for cancer treatment.

In addition to its role in cell proliferation, EN1 is also involved in a number of other cellular processes that are important for normal development and function. For example, EN1 has been shown to play a role in the development and maintenance of tissues, such as the skin and hair. It is also involved in the regulation of cell signaling pathways, which are important for the proper functioning of cells.

EN1 has also been implicated in a number of other diseases and disorders. For example, it has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's. It is also involved in the regulation of the immune system, which is important for the prevention of infections and diseases.

Despite the potential implications of EN1 as a drug target or biomarker, much more research is needed to fully understand its role in the body and its potential therapeutic uses. Currently, there are no approved drugs that are specifically targeting EN1. Researchers are actively working to develop new treatments that can specifically target EN1, and these efforts are likely to continue to be successful as the understanding of EN1's role in the body and its potential therapeutic uses continues to grow.

In conclusion, EN1 is a protein that has been shown to play a number of important roles in various cellular processes throughout the body. Its involvement in cell proliferation and the regulation of cellular signaling pathways makes it a potential drug target for a number of diseases. Further research is needed to fully understand its role in the body and its potential therapeutic uses.

Protein Name: Engrailed Homeobox 1

Functions: Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb

More Common Targets

EN2 | ENAH | ENAM | ENC1 | ENDOD1 | ENDOG | Endogenous Retrovirus group K Env polyprotein (ERVK) | Endogenous retrovirus group K member 25 Pol protein-like, transcript variant X1 | EndoGlyx-1 | Endoplasmic reticulum collagen prolyl 3-hydroxylation complex | Endothelin receptor | Endothelin-Converting Enzymes (ECE) | Endothiapepsin | ENDOU | ENDOV | ENG | ENGASE | ENHO | ENKD1 | ENKUR | ENO1 | ENO1-AS1 | ENO1P1 | ENO1P4 | ENO2 | ENO3 | ENO4 | ENOPH1 | eNoSC Complex | ENOSF1 | ENOX1 | ENOX1-AS2 | ENOX2 | ENPEP | ENPP1 | ENPP2 | ENPP3 | ENPP4 | ENPP5 | ENPP6 | ENPP7 | ENPP7P10 | ENPP7P12 | ENPP7P7 | ENSA | ENSAP2 | ENTHD1 | ENTPD1 | ENTPD1-AS1 | ENTPD2 | ENTPD3 | ENTPD3-AS1 | ENTPD4 | ENTPD5 | ENTPD6 | ENTPD7 | ENTPD8 | ENTR1 | ENTREP1 | ENTREP2 | ENTREP3 | env | ENY2 | EOGT | EOLA1 | EOLA1-DT | EOLA2 | EOLA2-DT | EOMES | EP300 | EP300-AS1 | EP400 | EP400P1 | EPAS1 | EPB41 | EPB41L1 | EPB41L1-AS1 | EPB41L2 | EPB41L3 | EPB41L4A | EPB41L4A-AS1 | EPB41L4A-DT | EPB41L4B | EPB41L5 | EPB42 | EPC1 | EPC2 | EPCAM | EPCAM-DT | EPDR1 | EPG5 | EPGN | EPHA1 | EPHA1-AS1 | EPHA10 | EPHA2 | EPHA2-AS1 | EPHA3 | EPHA4 | EPHA5