CD249: A Protein Involved in Many Biological Processes and Cancer Development

Target Name: ENPEP

NCBI ID: G2028

CD249: A Protein Involved in Many Biological Processes and Cancer Development

ENPEP (CD249 antigen), also known as CD249, is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is a member of the carbohydrate antigen 6 (CA6) family, which is characterized by the presence of a single constant region and a single variable region.

CD249 is a glycoprotein that consists of a single transmembrane domain and a cytoplasmic tail. It has a molecular weight of approximately 180 kDa and a pre-fusion molecular mass of approximately 160 kDa. CD249 is expressed in various tissues throughout the body, including the skin, hair, and nails, and is also found in the placenta, fetal brain, and heart.

CD249 is involved in many different biological processes in the body, including cell adhesion, migration, and invasion. It is a critical regulator of the migratory front, which is the outermost layer of the skin and other tissues and plays a key role in their development and maintenance.

CD249 has also been shown to be involved in many different types of cancer, including breast, ovarian, and prostate cancer. In these cancers, CD249 is often overexpressed and can serve as a drug target or biomarker. For example, some studies have shown that targeting CD249 with small molecules or antibodies has the potential to be an effective treatment for these cancers.

In addition to its potential as a drug target, CD249 has also been shown to be a useful biomarker for certain types of cancer. For example, some studies have shown that the level of CD249 in cancer cells can be used as a marker for the disease and can be used to track the effectiveness of certain treatments.

Overall, CD249 is a protein that is involved in many different biological processes in the body and has been shown to be involved in the development and progression of many types of cancer. Further research is needed to fully understand its role in these processes and to explore its potential as a drug target or biomarker.

Protein Name: Glutamyl Aminopeptidase

Functions: Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II

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