ETV1: Enriching Characterization of A Cell Signaling Protein (G2115)
ETV1: Enriching Characterization of A Cell Signaling Protein
ETV1 (ETS translocation variant 1 (isoform e)) is a gene that encodes a protein known as ETV1. ETV1 is a member of the ETS gene family, which is characterized by the presence of a unique transmembrane domain and a variable exon in the coding region. The ETS gene family is involved in various cellular processes, including cell signaling, DNA replication, and cell adhesion.
ETV1 is a splicing variant of the ETS gene, which means that it is one of several possible ways to generate the ETS protein. The most common splicing variant of ETS is ETS1, which is a full-length protein that consists of 254 amino acids. Other splicing variants of ETS include ETS2, which is a truncated protein that consists of 126 amino acids, and ETS3, which is a completely truncated protein that consists of only 4 amino acids.
ETV1 is a 21-kDa protein that is expressed in various tissues and organs, including brain, muscle, heart, and liver. It is involved in several cellular processes, including cell signaling, cell adhesion, and DNA replication.
One of the functions of ETV1 is its role in cell signaling. ETV1 has been shown to play a role in the regulation of cell proliferation and differentiation. It has been shown to promote the growth and survival of various cell types, and to play a role in the development of cancer.
In addition to its role in cell signaling, ETV1 is also involved in cell adhesion. ETV1 has been shown to be involved in the regulation of cell-cell adhesion, and to play a role in the development of various diseases, including cancer.
Another function of ETV1 is its role in DNA replication. ETV1 has been shown to be involved in the regulation of DNA replication, and to play a role in the development of cancer.
In conclusion, ETV1 is a gene that encodes a protein that is involved in several cellular processes, including cell signaling, cell adhesion, and DNA replication. As a result, it is a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of ETV1 in cellular processes and its potential as a drug.
Protein Name: ETS Variant Transcription Factor 1
Functions: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity)
More Common Targets
ETV2 | ETV3 | ETV3L | ETV4 | ETV5 | ETV6 | ETV7 | Eukaryotic translation initiation factor 2-alpha kinase | Eukaryotic translation initiation factor 2B | Eukaryotic translation initiation factor 3 (eIF-3) complex | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Eukaryotic Translation Initiation Factor 4E Binding Protein | EVA1A | EVA1A-AS | EVA1B | EVA1C | EVC | EVC2 | EVI2A | EVI2B | EVI5 | EVI5L | EVL | EVPL | EVPLL | EVX1 | EVX1-AS | EVX2 | EWSAT1 | EWSR1 | EXD1 | EXD2 | EXD3 | EXO1 | EXO5 | EXOC1 | EXOC1L | EXOC2 | EXOC3 | EXOC3-AS1 | EXOC3L1 | EXOC3L2 | EXOC3L4 | EXOC4 | EXOC5 | EXOC5P1 | EXOC6 | EXOC6B | EXOC7 | EXOC8 | Exocyst complex | EXOG | EXOGP1 | Exon junction complex | EXOSC1 | EXOSC10 | EXOSC10-AS1 | EXOSC2 | EXOSC3 | EXOSC4 | EXOSC5 | EXOSC6 | EXOSC7 | EXOSC8 | EXOSC9 | Exosome Complex | EXPH5 | EXT1 | EXT2 | EXTL1 | EXTL2 | EXTL2P1 | EXTL3 | EXTL3-AS1 | EYA1 | EYA2 | EYA3 | EYA4 | EYS | EZH1 | EZH2 | EZHIP | EZR | F10 | F11 | F11-AS1 | F11R | F12 | F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1