KLHL34: A Potential Drug Target and Biomarker (G257240)

Target Name: KLHL34

NCBI ID: G257240

KLHL34: A Potential Drug Target and Biomarker

Kelch-like 34 (KLHL34) is a protein that is expressed in various tissues, including the brain, heart, and kidneys, and is involved in a variety of cellular processes. Its unique structure and subcellular localization have led to its potential as a drug target and biomarker.

The protein KLHL34 is composed of 118 amino acid residues and has a calculated molecular weight of 19.5 kDa. It is characterized by a long extracellular domain that is involved in its cytoplasmic localization and by a short transmembrane domain that is involved in its intracellular localization. The transmembrane domain is composed of a single 伪-helix and is responsible for the formation of a monomeric state.

KLHL34 is expressed in a variety of tissues and is involved in a variety of cellular processes, including the regulation of cell adhesion, migration, and survival. For example, KLHL34 has been shown to be involved in the regulation of neuronal cell-cell adhesion and has been shown to play a role in the development of neurodegenerative diseases.

In addition to its involvement in cellular processes, KLHL34 is also a potential drug target. Its unique structure and subcellular localization make it an attractive target for small molecules that can modulate its activity. Additionally, its involvement in the regulation of cellular processes makes it a potential biomarker for a variety of diseases.

One of the potential benefits of targeting KLHL34 is its potential to modulate the activity of other proteins that are involved in the same cellular processes. This can lead to more targeted and effective therapies. For example, if KLHL34 is shown to play a role in the regulation of neurotransmitter release, targeting KLHL34 with small molecules that modulate neurotransmitter release could be an effective way to treat a variety of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and depression.

Another potential benefit of targeting KLHL34 is its potential to modulate the activity of KLHL34 itself. KLHL34 has been shown to play a role in the regulation of cellular processes and its activity may be modulated by small molecules that affect its structure or function. Targeting KLHL34 with small molecules that modulate its activity could be an effective way to treat a variety of diseases, including neurodegenerative diseases and cancer.

In conclusion, KLHL34 is a protein that is expressed in various tissues and is involved in a variety of cellular processes. Its unique structure and subcellular localization make it an attractive target for small molecules that can modulate its activity. Additionally, its involvement in the regulation of cellular processes makes it a potential biomarker for a variety of diseases and its potential as a drug target is a promising area of 鈥嬧?媟esearch. Further studies are needed to fully understand the role of KLHL34 in cellular processes and its potential as a drug target and biomarker .

Protein Name: Kelch Like Family Member 34

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