Unlocking The Potential of KLK4: A Protein with Interaction Potential

Target Name: KLK4

NCBI ID: G9622

Unlocking The Potential of KLK4: A Protein with Interaction Potential

KLK4 (Kratchmarion gene-related 4) is a gene that encodes a protein known as KLK4. KLK4 is a 21-kDa protein that is expressed in various tissues and cells throughout the body. It is a member of the KLK gene family, which is known for producing a variety of cytoplasmic proteins that play important roles in various cellular processes.

One of the unique features of KLK4 is its ability to interact with other proteins, particularly with the protein known as KLK7. KLK7 is a 22-kDa protein that is also a member of the KLK gene family. KLK4 and KLK7 can interact with each other , leading to the formation of a complex that is involved in various cellular processes.

In addition to its role in the KLK gene family, KLK4 is also a potential drug target. Its interaction with KLK7 makes it a promising target for small molecules that can modulate the activity of the two proteins. Furthermore, KLK4 has been shown to play a role in various cellular processes, including cell adhesion, migration, and invasion. This suggests that it may be a useful biomarker for the study of various diseases.

One of the challenges in studying KLK4 as a drug target is its relatively small size. KLK4 is only 21 kDa, which makes it difficult to produce sufficient quantities of the protein for experimental studies. However, researchers are working to overcome this challenge by developing new techniques for its production and purification.

Another potential challenge in studying KLK4 is its complex structure. KLK4 is a 21-kDa protein that contains a variety of different domains, including an N-terminal transmembrane domain, a coiled-coil domain, and a C-terminal T-loop. The The precise function of these different domains is not yet fully understood, and researchers are working to clarify their roles in the protein's activity.

Despite these challenges, researchers are actively pursuing studies of KLK4 as a drug target. They are using a variety of techniques, including biochemical, cellular, and mass spectrometry, to study the behavior of KLK4 in different cellular contexts. They are also using small molecules to identify potential modulators of the protein's activity.

In addition to its potential as a drug target, KLK4 is also a promising biomarker for the study of various diseases. Its interaction with KLK7 and its role in cell adhesion, migration, and invasion make it an attractive candidate for the development of new diagnostic tests or therapies for a variety of diseases.

Overall, KLK4 is a complex and fascinating protein that has the potential to revolutionize our understanding of cellular processes and disease. While there are still many challenges to be overcome, researchers are actively working to unlock the full potential of this protein, and its potential as a drug target and biomarker is an exciting area of 鈥嬧?媟esearch to explore.

Protein Name: Kallikrein Related Peptidase 4

Functions: Has a major role in enamel formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity)

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