Target Name: KRT13
NCBI ID: G3860
Other Name(s): K13 | keratin 13 | Keratin-13 | KRT13 variant 1 | WSN2 | cytokeratin 13 | Keratin 13, transcript variant 1 | K1C13_HUMAN | CK-13 | Cytokeratin 13 | Keratin, type I cytoskeletal 13 | CK13 | Keratin, type I cytoskeletal 13 isoform a | Cytokeratin-13 | keratin 13, type I

KRT13: A Protein Implicated in Cancer and Other Diseases

KRT13 (K13), also known as human kallikrein-related peptidase 13, is a protein that is expressed in various tissues throughout the body. It is a 13-kDa protein that belongs to the serine proteases group 7 family. KRT13 is highly conserved and has a single known gene that is located on chromosome 11.1.

KRT13 is involved in the regulation of various physiological processes in the body, including the balance of fluids and electrolytes, cell signaling, and tissue repair. It is a key protein in the regulation of extracellular matrix (ECM) degradation, which is critical for tissue repair and regeneration.

KRT13 has also been shown to play a role in the development and progression of various diseases, including cancer. For example, KRT13 has been shown to be overexpressed in various types of cancer, including breast, ovarian, and prostate cancer. This suggests that KRT13 may be a potential drug target or biomarker for these diseases.

In addition to its role in cancer, KRT13 has also been shown to be involved in the development of other diseases. For example, KRT13 has been linked to the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, KRT13 has been shown to be involved in the development of fibrosis, which is a complex condition that can lead to the loss of tissue mass and function.

KRT13 is also involved in the regulation of cellular signaling pathways that are critical for cell growth, differentiation, and survival. For example, KRT13 has been shown to play a role in the regulation of the TGF-β pathway, which is a critical pathway for cell growth and differentiation.

KRT13 is a 13-kDa protein that is highly conserved and has a single known gene that is located on chromosome 11.1. It is involved in the regulation of various physiological processes in the body, including the balance of fluids and electrolytes, cell signaling, and tissue repair. KRT13 has also been shown to play a role in the development and progression of various diseases, including cancer. Additionally, KRT13 is involved in the regulation of cellular signaling pathways that are critical for cell growth, differentiation, and survival.

Protein Name: Keratin 13

Functions: Type 1 keratin (Probable). Maintains postnatal tongue mucosal cell homeostasis and tissue organization in response to mechanical stress, potentially via regulation of the G1/S phase cyclins CCNE1 and CCNE2 (By similarity)

More Common Targets

KRT14 | KRT15 | KRT16 | KRT16P1 | KRT16P2 | KRT16P3 | KRT16P6 | KRT17 | KRT17P1 | KRT17P2 | KRT17P3 | KRT17P5 | KRT17P7 | KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16