Targeting KRT18P4: A Potential Drug Or Biomarker for Cancer (G391256)
Targeting KRT18P4: A Potential Drug Or Biomarker for Cancer
KRT18P4 (dJ963K23.1) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer. The gene is located on chromosome 963 and has been identified as a key regulator of the cell cycle, specifically the G1 phase.
The G1 phase is a critical stage in the cell cycle where the cell prepares for cell division by going through the S phase. KRT18P4 plays a crucial role in regulating the G1 phase by ensuring that the cell completes its necessary checks and balances before entering the S phase.
Research has shown that KRT18P4 is often expressed at different levels in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, studies have shown that inhibiting KRT18P4 can lead to cell cycle arrest and a reduction in cancer cell proliferation.
This lead has led researchers to consider KRT18P4 as a potential drug target or biomarker for cancer treatment. By targeting KRT18P4, researchers hope to inhibit the cell cycle and disrupt the ability of cancer cells to divide and proliferate.
One approach to targeting KRT18P4 is through the use of small molecules, such as drugs that inhibit the activity of KRT18P4. These drugs can be administered to cancer cells to disrupt their ability to enter the S phase and continue their cell cycle.
Another approach to targeting KRT18P4 is through the use of antibodies that recognize and target the protein. These antibodies can be used to specifically bind to KRT18P4 and inhibit its activity, leading to a reduction in cell cycle progression and a decrease in cancer cell proliferation.
In addition to its potential as a drug target or biomarker, KRT18P4 has also been identified as a potential biomarker for cancer. The KRT18P4 gene has been shown to be expressed at different levels in various types of cancer, including breast, ovarian, and colorectal cancer. Additionally, studies have shown that inhibiting KRT18P4 can lead to significant reductions in cancer cell proliferation, which could be used as a biomarker for cancer diagnosis and treatment.
Overall, KRT18P4 is a promising drug target or biomarker for cancer treatment. Further research is needed to fully understand its potential and develop effective treatments.
Protein Name: Keratin 18 Pseudogene 4
More Common Targets
KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1