KRT18P48: A Potential Drug Target and Biomarker (G340598)

KRT18P48: A Potential Drug Target and Biomarker

Keratin is a protein that is found in the hair, nails, and skin. It is a complex protein that plays a vital role in the structure and function of these tissues. One of the proteins that is known as Keratin 18 (K18) is a pseudogene that is expressed in the hair follicles, but is also found in other tissues, including the skin and the nervous system. KRT18P48, also known as K18, is a potential drug target and biomarker that has been identified for its role in the development and progression of various diseases, including cancer.

The Hair Follicle

The hair follicle is the structure that produces the hair. It is made up of several layers of cells, including the epithelial, interfollicular, and terminal cells. The epithelial cells are the outer cells of the follicle, and they produce the sebum that helps to keep the hair moisturized and prevent dryness. The interfollicular cells are the cells between the epithelial cells, and they produce the growth factors that help to promote hair growth. The terminal cells are the inner cells of the follicle, and they produce the Hair follicle cycle protein 1 (HFC-1), which is a key regulator of the hair follicle cycle.

KRT18P48 is a pseudogene that is expressed in the epithelial cells of the hair follicle. It is a small gene that contains only 18 amino acids. It is located on the X chromosome and has a conserved structure that is similar to other proteins that are known as pseudogenes, which are genes that have a conserved sequence but do not have a functional gene.

KRT18P48 and Hair Loss

KRT18P48 has been shown to be involved in the development and progression of hair loss. Studies have shown that individuals with certain genetic mutations, such as the androgen receptor-伪 (ARA) gene mutation, are at increased risk of developing male pattern baldness, which is a common condition that causes the hair to become thinner and may eventually fall out. The ARA gene is located on the X chromosome and is responsible for the production of androgens, which are male hormones.

Research has also shown that KRT18P48 is involved in the regulation of the hair follicle cycle, which is the process by which the hair follicles produce new hair. Studies have shown that individuals with certain genetic mutations, such as the missense mutation in the K18 gene, are at increased risk of developing hair loss. This mutation has been shown to disrupt the normal function of the hair follicle cycle, leading to the production of too many hair follicles and the death of the hair cells.

Drug Targeting

KRT18P48 has been identified as a potential drug target for the treatment of various diseases, including cancer. Studies have shown that KRT18P48 is expressed in various tissues and that it plays a role in the development and progression of various diseases, including cancer. For example, studies have shown that KRT18P48 is expressed in the breast tissue and that it is involved in the regulation of cell growth and division.

In addition, KRT18P48 has also been shown to be involved in the regulation of the immune system. Studies have shown that KRT18P48 is expressed in the immune cells and that it plays a role in the regulation of immune cell function. This suggests that KRT18P48 may be a useful biomarker for the diagnosis and treatment of various immunodeficiency

Protein Name: Keratin 18 Pseudogene 48

More Common Targets

KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41 | KRT8P44 | KRT8P45 | KRT8P46 | KRT8P47 | KRT8P48 | KRT8P49 | KRT8P5 | KRT8P7 | KRT8P8 | KRT8P9 | KRT9 | KRT90P | KRTAP1-1 | KRTAP1-3 | KRTAP1-4 | KRTAP1-5 | KRTAP10-1 | KRTAP10-10 | KRTAP10-11 | KRTAP10-12 | KRTAP10-2 | KRTAP10-3