Target Name: KRT17P3
NCBI ID: G729682
Other Name(s): keratin 17 pseudogene 3 | Keratin 17 pseudogene 3

KRT17P3: A Potential Drug Target and Biomarker

Keratin 17 (K17) is a well-known protein that plays a crucial role in the maintenance of hair and nails. The K17 gene has four exons, and three pseudogenes have been identified: K17P1, K17P2, and K17P3. In this article, we will focus on K17P3, which has potential as a drug target or biomarker.

K17P3 is a 193-amino acid protein that is highly conserved in both humans and animals. It is expressed in various tissues, including skin, scalp, and hair follicles. K17P3 is a key component of the hair matrix, and it helps in the development, growth, and maintenance of hair.

K17P3 has been shown to play a critical role in the regulation of hair growth and differentiation. It is involved in the formation of the growth plug, which is the first stage in the development of a hair follicle. The growth plug is a critical structure that provides essential signals for the formation of the hair matrix. K17P3 is involved in the regulation of these signals, which are crucial for the growth and differentiation of hair follicles into terminal units.

In addition to its role in hair growth and development, K17P3 has also been shown to be involved in the regulation of cell signaling pathways. It is a potent inhibitor of the androgen receptor (AR), which is a key transcription factor that regulates the expression of genes involved in male characteristics. The AR is involved in the development and maintenance of male traits, including the growth and development of facial hair, and the development of prostate gland.

The androgen receptor is also involved in the regulation of various signaling pathways that are involved in the development and maintenance of cancer. Therefore, it is of great interest to investigate the role of K17P3 in the regulation of androgen signaling pathways, as this may have implications for the development of prostate cancer.

K17P3 has also been shown to play a role in the regulation of cell adhesion and migration. It is involved in the formation of tight junctions, which are critical for the separation of cells in various tissues. tight junctions are also involved in the regulation of ion and solute transport, as well as the regulation of cell signaling pathways.

In conclusion, K17P3 is a well-known protein that plays a critical role in the maintenance of hair and nails. It is involved in the regulation of hair growth and development, as well as the regulation of cell signaling pathways. The potential drug target status of K17P3 makes it an attractive candidate for further investigation. Further studies are needed to fully understand the role of K17P3 in the regulation of hair growth and development, as well as its potential as a drug target.

Protein Name: Keratin 17 Pseudogene 3

More Common Targets

KRT17P5 | KRT17P7 | KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37