KRT17P7: A Potential Drug Target and Biomarker (G339258)
KRT17P7: A Potential Drug Target and Biomarker
Keratin 17 (K17) is a cytoskeleton protein that plays a crucial role in the structure and function of hair and nails. The K17 gene has four exons, and three splice variants have been identified. One of these variants, KRT17P7, has been identified as a potential drug target and biomarker.
The KRT17P7 gene encodes a 21-kDa protein that is involved in the formation of the intercellular matrix (ICM) in hair and nail growth. The ICM is a complex matrix of proteins that provides structural support and contributes to the mechanical properties of the hair and nail. The KRT17P7 protein is one of the components of the ICM and is involved in the formation of the matrix.
KRT17P7 has been shown to play a critical role in the development and maintenance of hair and nails. Studies have shown that the KRT17P7 gene is highly expressed in hair and nail follicles, and that the KRT17P7 protein is highly concentrated in the ICM of growing hair and nails. In addition, the KRT17P7 protein has been shown to play a critical role in the regulation of cell proliferation and differentiation in the ICM.
The potential drug target for KRT17P7 is the regulation of cell proliferation and differentiation in the ICM. Cancer cells have been shown to take advantage of changes in the ICM that can occur due to various conditions, such as aging, trauma, or genetic mutations. The KRT17P7 protein has been shown to play a critical role in the regulation of cell proliferation and differentiation in the ICM, and it is possible that it may be a useful target for cancer therapies.
In addition to its role in the ICM, KRT17P7 has also been shown to play a critical role in the regulation of cell adhesion. The ICM is a complex matrix of proteins that helps to maintain the integrity of the blood vessels that supply the scalp and hair. The KRT17P7 protein is involved in the regulation of cell adhesion to the ICM, which is important for the maintenance of blood vessel integrity and the growth of hair and nails.
The potential biomarker for KRT17P7 is the detection of KRT17P7 expression in hair and nail samples. This can be done using techniques such as qRT-PCR, western blotting, and immunofluorescence. The expression of KRT17P7 in hair and nail samples can be used as a biomarker for various conditions, such as cancer, trauma, or aging. In addition, the expression of KRT17P7 in the ICM can be used as a biomarker for the regulation of cell proliferation and differentiation.
In conclusion, KRT17P7 is a potential drug target and biomarker that has been identified based on its involvement in the regulation of cell proliferation and differentiation in the ICM. The KRT17P7 protein plays a critical role in the formation of the ICM in hair and nail growth, and it is possible that it may be a useful target for cancer therapies. Further research is needed to fully understand the role of KRT17P7 in the regulation of cell proliferation and differentiation in the ICM, as well as its potential as a biomarker.
Protein Name: Keratin 17 Pseudogene 7
More Common Targets
KRT18 | KRT18P1 | KRT18P12 | KRT18P13 | KRT18P16 | KRT18P17 | KRT18P19 | KRT18P22 | KRT18P23 | KRT18P24 | KRT18P27 | KRT18P28 | KRT18P29 | KRT18P31 | KRT18P33 | KRT18P34 | KRT18P4 | KRT18P40 | KRT18P41 | KRT18P42 | KRT18P44 | KRT18P48 | KRT18P49 | KRT18P5 | KRT18P50 | KRT18P51 | KRT18P55 | KRT18P59 | KRT18P6 | KRT18P62 | KRT19 | KRT19P2 | KRT19P3 | KRT2 | KRT20 | KRT222 | KRT23 | KRT24 | KRT25 | KRT26 | KRT27 | KRT28 | KRT3 | KRT31 | KRT32 | KRT33A | KRT33B | KRT34 | KRT35 | KRT36 | KRT37 | KRT38 | KRT39 | KRT4 | KRT40 | KRT42P | KRT5 | KRT6A | KRT6B | KRT6C | KRT7 | KRT7-AS | KRT71 | KRT72 | KRT73 | KRT73-AS1 | KRT74 | KRT75 | KRT76 | KRT77 | KRT78 | KRT79 | KRT8 | KRT80 | KRT81 | KRT82 | KRT83 | KRT84 | KRT85 | KRT86 | KRT87P | KRT89P | KRT8P10 | KRT8P11 | KRT8P12 | KRT8P14 | KRT8P16 | KRT8P17 | KRT8P18 | KRT8P22 | KRT8P23 | KRT8P25 | KRT8P26 | KRT8P29 | KRT8P3 | KRT8P33 | KRT8P36 | KRT8P37 | KRT8P39 | KRT8P41
