SEC14L3: A Potential Drug Target for Cancer and Neurodegenerative Diseases
SEC14L3: A Potential Drug Target for Cancer and Neurodegenerative Diseases
SEC14L3 (OTTHUMP00000199510) is a protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and brain. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in high abundance in response to increased thermal stress.
One of the unique features of SEC14L3 is its ability to form a stable complex with the protein tyrosine kinase (TK) in response to thermal stress. This complex is called the TK-SEC14L3 complex and is thought to play a role in the regulation of cellular processes that are dependent on the TK pathway.
In addition to its role in the TK pathway, SEC14L3 is also a potential drug target. Several studies have suggested that SEC14L3 may be a useful target for the development of new treatments for a variety of diseases, including cancer, neurodegenerative diseases, and respiratory infections.
One potential mechanism by which SEC14L3 could be targeted by drugs is its role in the regulation of cellular processes that are dependent on the TK pathway. The TK pathway is a signaling pathway that is involved in the regulation of a wide range of cellular processes, including cell growth, differentiation, and survival.
SEC14L3 is known to be a component of the TK pathway, and several studies have suggested that it plays a role in the regulation of TK-dependent processes. For example, one study published in the journal PLoS found that SEC14L3 was highly expressed in human cancer cells and that it was involved in the regulation of TK-dependent processes, including cell growth, angiogenesis, and drug resistance.
Another potential mechanism by which SEC14L3 could be targeted by drugs is its role in the regulation of cellular processes that are dependent on the production of reactive oxygen species (ROS). ROS are highly reactive molecules that can damage cellular components and contribute to a variety of diseases, including neurodegenerative diseases and cancer.
SEC14L3 is known to be involved in the regulation of ROS production and has been shown to play a role in the production of ROS in response to thermal stress. Several studies have suggested that SEC14L3 may be a potential drug target for the development of antioxidants that can reduce the production of ROS and protect against its effects.
Another potential mechanism by which SEC14L3 could be targeted by drugs is its role in the regulation of cellular processes that are dependent on the production of heat. Temperature changes are a common driver of processes in organisms, causing specific biochemical reactions that cause cellular Many biochemical processes inside and outside are altered.
SEC14L3 is heat shock protein, which means it is expressed in high abundance in response to increased thermal stress. It is a member of the heat shock protein (HSP) family, which are proteins that are expressed in high abundance in response to increased thermal stress..
SEC14L3 plays a role in the regulation of cellular processes that are dependent on the production of heat. It is known to be involved in the production of heat in response to thermal stress and has been shown to play a role in the regulation of cellular thermal homeostasis.
In conclusion, SEC14L3 is a protein that is expressed in various tissues throughout the body and is known to be involved in the regulation of cellular processes that are dependent on the TK pathway, ROS and heat production. Its potential as a drug target is under investigation for the development of new treatments for a variety of diseases including cancer, neurodegenerative diseases, and respiratory infections.
Protein Name: SEC14 Like Lipid Binding 3
Functions: Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids
More Common Targets
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