MACC1: Putative Binding Protein Interacting with ICAM-1 (G346389)

Target Name: MACC1

NCBI ID: G346389

MACC1: Putative Binding Protein Interacting with ICAM-1

MACC1 (Putative binding protein 7a5) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and kidneys. It is a member of the MACC (membrane binding protein) family, which is known for its ability to interact with membrane receptors. MACC1 is also a putative binding protein, which means it is a protein that can bind to a specific protein called ICAM-1 (Immunosuppressive cell adhesion molecule 1).

ICAM-1 is a protein that is expressed in various tissues throughout the body, including the immune system and the bloodstream. It is a cell adhesion molecule, which means it helps to stick cells together and form tissues. ICAM-1 is also known as CD51, and it is a protein that is expressed in high levels in diseases such as cancer, neurodegenerative diseases, and autoimmune disorders.

MACC1 is known to interact with ICAM-1 in a variety of ways. For one, MACC1 can bind to ICAM-1 on the surface of immune cells, such as T cells and macrophages. This interaction between MACC1 and ICAM-1 can help to regulate the immune response and may be important for diseases such as cancer and autoimmune disorders.

Another way that MACC1 can interact with ICAM-1 is through a process called complementation. Complementation is a process in which two proteins work together to enhance each other's functions. MACC1 and ICAM-1 can complement each other in several ways, including through their ability to interact with each other's cell surfaces and through their ability to interact with other proteins that are involved in the immune response.

In addition to its role in immune regulation, MACC1 is also known to play a role in the development and progression of certain diseases. For example, MACC1 is often expressed in the brains of people with Alzheimer's disease, and it is thought to contribute to the development of this disease. Additionally, MACC1 is also expressed in the hearts of people with heart failure, and it is thought to contribute to the development and progression of this disease.

MACC1 is also a potential drug target in several ways. For one, MACC1 can be a target for small molecules that can modulate its function and activity. Additionally, MACC1 can be used as a biomarker for several diseases, including Alzheimer's disease, cancer, and heart failure.

In conclusion, MACC1 is a protein that is expressed in various tissues throughout the body and is known for its ability to interact with ICAM-1. MACC1 is a putative binding protein that can bind to ICAM-1, and it is involved in a variety of processes in the immune system and in the development and progression of certain diseases. Additionally, MACC1 is a potential drug target and can be used as a biomarker for several diseases. Further research is needed to fully understand the role of MACC1 in disease and to develop effective treatments.

Protein Name: MET Transcriptional Regulator MACC1

Functions: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo

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