MAGEA11: A Potential Drug Target for Various Diseases (G4110)

Target Name: MAGEA11

NCBI ID: G4110

MAGEA11: A Potential Drug Target for Various Diseases

MAGEA11, a member of the MAGE family, is a protein that is expressed in various tissues of the body, including the lungs, heart, liver, and brain. It is a key regulator of cell growth, development, and survival, and is involved in the processes that maintain tissue homeostasis and promote regeneration.

Recent studies have identified MAGEA11 as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because MAGEA11 has been shown to play a role in the regulation of cellular processes that are often disrupted in these conditions, such as cell proliferation, migration, and survival.

One of the key reasons for the potential of MAGEA11 as a drug target is its ability to interact with a variety of signaling pathways. MAGEA11 has been shown to be involved in several different signaling pathways, including the TGF-β pathway, the Wnt pathway, and the Hedgehog pathway. These pathways are involved in the regulation of cell growth, differentiation, and survival, and are often disrupted in various diseases.

In addition to its role in signaling pathways, MAGEA11 has also been shown to be involved in the regulation of cellular processes that are important for tissue homeostasis. For example, MAGEA11 has been shown to play a role in the regulation of cell proliferation and differentiation, as well as in the formation of tissues such as blood vessels and heart muscle.

MAGEA11 has also been shown to be involved in the regulation of cellular processes that are important for immune function. For example, MAGEA11 has been shown to play a role in the regulation of T cell development and function, as well as in the regulation of inflammation.

Given its involvement in multiple signaling pathways and its role in the regulation of cellular processes that are important for tissue homeostasis and immune function, MAGEA11 is a promising drug target for the treatment of various diseases. Future studies are likely to continue to investigate the potential of MAGEA11 as a drug target, and to develop new approaches to the treatment of diseases that are caused by the disruption of MAGEA11 signaling.

Protein Name: MAGE Family Member A11

Functions: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression

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