Target Name: MACIR
NCBI ID: G90355
Other Name(s): Macrophage immunometabolism regulator | UPF0684 protein C5orf30 | MACIR_HUMAN | Chromosome 5 open reading frame 30 | C5orf30 | macrophage immunometabolism regulator | CE030_HUMAN | FLJ25291 | UNC119-binding protein C5orf30 | Macrophage immunometabolism regulator, transcript variant 1 | OTTHUMP00000158932 | MACIR variant 1

MACIR: A Protein with Potential for Chronic Inflammation Treatment

Macrophage immunometabolism regulator (MACIR) is a protein that plays a crucial role in the regulation of macrophage function. Macrophages are a type of white blood cell that are responsible for fighting off infections and other harmful substances in the body. They are an essential part of the immune system and are able to recognize and destroy foreign particles, such as bacteria and viruses, that may have entered the body. However, there is a problem with macrophages. They can sometimes become overactive and cause inflammation, a condition known as chronic inflammation. This can lead to a range of health problems, including heart disease, cancer, and autoimmune disorders. MACIR is a protein that has the potential to be a drug target or biomarker for these conditions.

MACIR and Chronic Inflammation

Chronic inflammation is a serious problem that can lead to a range of health problems. It is characterized by the persistent activation of immune cells and the production of inflammatory cytokines. These cytokines can cause a range of symptoms, including pain, swelling, and redness. Chronic inflammation can also lead to the development of chronic diseases, such as heart disease, cancer, and autoimmune disorders.

MACIR is involved in the regulation of macrophage function and has the potential to be a drug target or biomarker for chronic inflammation. It is a protein that is expressed in macrophages and is involved in the metabolism of a variety of macrophage-derived products, including cytokines and chemokines. MACIR has been shown to play a role in the regulation of cytokine production and has been shown to interact with a variety of different cytokines, including T-cell cytokines and monocytes.

MACIR and Therapeutic Strategies for Chronic Inflammation

The treatment of chronic inflammation can be a difficult and expensive process. Currently, there are few treatments that are effective in treating this condition. Many of the treatments that are available for chronic inflammation are focused on managing symptoms rather than treating the underlying cause. This is a problem because chronic inflammation can lead to a range of serious health problems, including heart disease, cancer, and autoimmune disorders.

MACIR has the potential to be a drug target or biomarker for the treatment of chronic inflammation. If it is possible to target MACIR with small molecules or other compounds, it may be possible to treat chronic inflammation and improve the quality of life for people with this condition. For example, researchers have shown that inhibiting MACIR can be an effective way to reduce inflammation and improve the symptoms of chronic inflammation.

MACIR as a Biomarker

MACIR is also a protein that has the potential to be used as a biomarker for chronic inflammation. MACIR is expressed in macrophages and has been shown to play a role in the regulation of cytokine production. This makes MACIR an attractive target for researchers who are interested in the development of biomarkers for chronic inflammation. If MACIR can be effectively targeted with small molecules or other compounds, it may be possible to use MACIR as a diagnostic tool or as a target for therapeutic intervention.

MACIR as a Drug Target

MACIR is also a protein that has the potential to be used as a drug target for chronic inflammation. MACIR is involved in the regulation of cytokine production and has been shown to interact with a variety of different cytokines. This makes MACIR an attractive target for researchers who are interested in the development of drugs for chronic inflammation. If it is possible to develop compounds that specifically target MACIR, it may be possible to treat chronic inflammation and improve the quality of life for people with this condition.

Conclusion

MACIR is a protein that has the potential to be a drug target or biomarker for the treatment of chronic inflammation. MACIR is involved in the regulation of macrophage function and has been shown to play

Protein Name: Macrophage Immunometabolism Regulator

Functions: Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages (PubMed:30659109). The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis (PubMed:30659109). May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B (PubMed:22085962). May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells (PubMed:22085962)

More Common Targets

MACO1 | MACORIS | MACROD1 | MACROD2 | MACROD2-AS1 | MACROH2A1 | MACROH2A2 | MAD1L1 | MAD2L1 | MAD2L1BP | MAD2L2 | MADCAM1 | MADD | MAEA | MAEL | MAF | MAF1 | MAFA | MAFA-AS1 | MAFB | MAFF | MAFG | MAFIP | MAFK | MAFTRR | MAG | MAGEA1 | MAGEA10 | MAGEA11 | MAGEA12 | MAGEA13P | MAGEA2 | MAGEA2B | MAGEA3 | MAGEA4 | MAGEA5P | MAGEA6 | MAGEA7P | MAGEA8 | MAGEA9 | MAGEA9B | MAGEB1 | MAGEB10 | MAGEB16 | MAGEB17 | MAGEB18 | MAGEB2 | MAGEB3 | MAGEB4 | MAGEB5 | MAGEB6 | MAGEB6B | MAGEC1 | MAGEC2 | MAGEC3 | MAGED1 | MAGED2 | MAGED4 | MAGED4B | MAGEE1 | MAGEE2 | MAGEF1 | MAGEH1 | MAGEL2 | MAGI1 | MAGI1-AS1 | MAGI1-IT1 | MAGI2 | MAGI2-AS3 | MAGI3 | MAGIX | MAGOH | MAGOH-DT | MAGOHB | MAGT1 | MAIP1 | MAJIN | Major histocompatibility complex (MHC) antigen | Major Histocompatibility Complex Class I | Major histocompatibility complex class II antigens | MAK | MAK16 | MAL | MAL2 | MALAT1 | Malate dehydrogenase | MALL | MALLP2 | MALRD1 | MALSU1 | MALT1 | MAMDC2 | MAMDC2-AS1 | MAMDC4 | MAML1 | MAML2 | MAML3 | MAMLD1 | MAMSTR | MAN1A1