KIR2DS1: A Protein Involved in Immune Function and Cancer Development
KIR2DS1: A Protein Involved in Immune Function and Cancer Development
KIR2DS1 (KI2S1_HUMAN) is a protein that is expressed in most tissues of the human body. It is a key regulator of the immune response and has been implicated in a number of diseases, including cancer. In recent years, researchers have been interested in studying KIR2DS1 as a potential drug target or biomarker because of its unique structure and biology.
The KIR2DS1 protein is composed of 251 amino acid residues and has a molecular weight of 31 kDa. It is located in the cytoplasm and is involved in the regulation of various cellular processes, including cell adhesion, migration, and the response to stimuli. KIR2DS1 is a G protein-coupled receptor (GPCR), which means that it interacts with intracellular signaling molecules that are derived from the G protein family.
KIR2DS1 has been shown to play a role in the regulation of immune cell function and has been implicated in the development and progression of a number of diseases. For example, KIR2DS1 has been shown to be involved in the regulation of T cell development and function. KIR2DS1 has been shown to promote the growth and survival of T cells, which are a critical component of the immune system.
In addition to its role in T cell development, KIR2DS1 has also been shown to be involved in the regulation of cell signaling pathways that are important for the growth and survival of cancer cells. For example, KIR2DS1 has been shown to play a role in the regulation of the PI3K/Akt signaling pathway, which is important for the growth and survival of cancer cells.
KIR2DS1 has also been shown to be involved in the regulation of cell adhesion and migration. For example, KIR2DS1 has been shown to promote the adhesion of cancer cells to the extracellular matrix (ECM), which is important for the development and progression of cancer. In addition, KIR2DS1 has been shown to play a role in the regulation of cell migration, which is important for the formation of cancer stem cells.
In conclusion, KIR2DS1 is a unique and highly-regulated protein that has important roles in the regulation of immune cell function and the development and progression of cancer. As a potential drug target or biomarker, KIR2DS1 is of great interest to researchers because of its unique structure and biology. Further research is needed to fully understand the role of KIR2DS1 in these processes and to develop effective treatments for a variety of diseases.
Protein Name: Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Short Cytoplasmic Tail 1
Functions: Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells
More Common Targets
KIR2DS2 | KIR2DS3 | KIR2DS4 | KIR2DS5 | KIR3DL1 | KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4 | KLHDC7A | KLHDC7B | KLHDC7B-DT | KLHDC8A | KLHDC8B | KLHDC9 | KLHL1 | KLHL10 | KLHL11 | KLHL12 | KLHL13 | KLHL14 | KLHL15 | KLHL17 | KLHL18 | KLHL2 | KLHL20 | KLHL21 | KLHL22 | KLHL23 | KLHL24 | KLHL25 | KLHL26 | KLHL28 | KLHL29 | KLHL3 | KLHL30 | KLHL30-AS1 | KLHL31 | KLHL32 | KLHL33 | KLHL34 | KLHL35 | KLHL36 | KLHL38 | KLHL4 | KLHL40 | KLHL41 | KLHL42 | KLHL5 | KLHL6 | KLHL7 | KLHL7-DT | KLHL8 | KLHL9 | KLK1 | KLK10 | KLK11