TM6SF1: A Drug Target / Disease Biomarker (G53346)

Target Name: TM6SF1

NCBI ID: G53346

TM6SF1: A Drug Target / Disease Biomarker

TM6SF1 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of transmembrane protein (SMP) and is characterized by the presence of a unique transmembrane region and a cytoplasmic tail. TM6SF1 has been identified as a potential drug target and has been shown to play a role in a variety of biological processes, including cell signaling, neurodegeneration, and diseases such as Alzheimer's and Parkinson's.

TM6SF1 functions as a negative regulator of the protein kinase PDK4. PDK4 is a key enzyme that regulates cell signaling and is involved in the development and progression of many diseases, including cancer, neurodegeneration, and psychiatric disorders. TM6SF1 helps to regulate the activity of PDK4 and thereby controls the growth and survival of cells.

In addition to its role in cell signaling, TM6SF1 is also involved in the regulation of inflammation and immune responses. It has been shown to play a key role in the regulation of T cell responses and has been implicated in the development of autoimmune diseases. TM6SF1 has also been shown to be involved in the regulation of inflammation and has been implicated in the development of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

In neurodegeneration, TM6SF1 has been shown to play a role in the regulation of neurotransmitter release and the maintenance of neural circuitry. It has been shown to be involved in the development of neurodegenerative diseases such as Alzheimer's and Parkinson's and has been shown to protect against neurodegeneration in animal models of these diseases. TM6SF1 has also been shown to be involved in the regulation of pain perception and has been implicated in the development of chronic pain.

In diseases such as cancer, TM6SF1 has been shown to play a role in the regulation of cell proliferation and the development of cancer. It has been shown to be involved in the development of many types of cancer, including breast, lung, and ovarian cancer. TM6SF1 has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die when they are no longer needed.

Overall, TM6SF1 is a protein that has been shown to play a role in a variety of biological processes and has been identified as a potential drug target. Further research is needed to fully understand the role of TM6SF1 in disease and to develop effective treatments.

Protein Name: Transmembrane 6 Superfamily Member 1

Functions: May function as sterol isomerase

More Common Targets