DHX29: A Drug Target / Disease Biomarker (G54505)

Target Name: DHX29

NCBI ID: G54505

DHX29: A Drug Target / Disease Biomarker

DHX29 is a non-coding RNA molecule that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and expression pattern make it an attractive target for researchers to study and develop new treatments.

DHX29 is a member of the HAX family of non-coding RNAs, which are known for their ability to regulate gene expression and play a role in post-transcriptional gene regulation. DHX29 is characterized by its unique 29 base pair length and its ability to form a double-stranded RNA structure.

DHX29 has been shown to play a role in various cellular processes, including cell growth, apoptosis, and transcriptional regulation. It has been shown to be involved in the regulation of cell cycle progression, and to play a role in the detoxification of environmental toxins.

DHX29 has also been shown to be involved in the regulation of gene expression in response to various stimuli, including drugs and diseases. For example, studies have shown that DHX29 can be regulated by drugs such as taxanes, which are commonly used to treat cancer. Additionally, DHX29 has been shown to be regulated by diseases such as neurodegenerative disorders, where its expression is often decreased or absent.

DHX29's unique structure and expression pattern make it an attractive target for researchers to study and develop new treatments. Its small size and stability make it easy to manipulate, and its role in various cellular processes makes it a potential candidate for drug targeting.

In conclusion, DHX29 is a promising drug target or biomarker for various diseases. Further research is needed to fully understand its role in cellular processes and its potential as a therapeutic target.

Protein Name: DExH-box Helicase 29

Functions: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity

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