Target Name: SCYL1
NCBI ID: G57410
Other Name(s): SCY1-like, kinase-like 1 | OTTHUMP00000232621 | SCYL1_HUMAN | likely ortholog of mouse N-terminal kinase-like protein | OTTHUMP00000232632 | SCYL1 variant A | Teratoma-associated tyrosine kinase | NTKL | OTTHUMP00000232620 | telomerase regulation-associated protein | OTTHUMP00000232619 | SCY1-like protein 1 | teratoma-associated tyrosine kinase | OTTHUMP00000232737 | Telomerase transcriptional elements-interacting factor | N-terminal kinase-like protein (isoform A) | N-terminal kinase-like protein | P105 | TRAP | SCY1 like pseudokinase 1 | TEIF | coated vesicle-associated kinase of 90 kDa | GKLP | Telomerase transcriptional element-interacting factor | OTTHUMP00000232618 | telomerase transcriptional elements-interacting factor | NKTL | TAPK | HT019 | SCY1 like pseudokinase 1, transcript variant A | Likely ortholog of mouse N-terminal kinase-like protein | CVAK90 | Coated vesicle-associated kinase of 90 kDa | Telomerase regulation-associated protein | OTTHUMP00000232622 | SCAR21 | MGC78454

Regulation of PKG Activity and Cancer Development By SCYL1

SCYL1 (SCY1-like, kinase-like 1) is a protein that is expressed in various tissues and cells throughout the body. It is a member of the SCYL family, which includes several similar proteins that play important roles in cellular signaling pathways. One of the key functions of SCYL1 is its role in cell signaling, particularly in the regulation of protein kinase (PKG) activity.

The SCYL1 protein is composed of 215 amino acid residues and has a calculated molecular mass of 31.1 kDa. It is expressed in a variety of tissues, including muscle, heart, brain, and kidney. It is also expressed in various cell types, including epithelial cells, neurons, and immune cells.

SCYL1 is a protein that is known to play a role in the regulation of PKG activity. PKG is a protein that is involved in the regulation of cellular signaling pathways, including many that are involved in cell growth, differentiation, and survival. SCYL1 is thought to regulate the activity of PKG by interacting with its catalytic active site, which is the site on the protein where the enzyme catalyzes its substrate.

SCYL1 is also known to play a role in the regulation of cellular signaling pathways that are involved in the development and progression of cancer. For example, studies have shown that SCYL1 is involved in the regulation of the angiogenesis that occurs during the development of cancer. In addition, SCYL1 is also thought to be involved in the regulation of the metastasis that occurs when cancer cells spread from the primary tumor to other parts of the body.

In addition to its role in cell signaling and cancer development, SCYL1 is also thought to play a role in the regulation of cellular processes that are involved in inflammation and stress responses. For example, studies have shown that SCYL1 is involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾, that are involved in the regulation of inflammation and stress responses.

Overall, SCYL1 is a protein that is involved in a variety of cellular processes that are important for the regulation of cell signaling, cancer development, and inflammation. As a result, it is a potential drug target or biomarker for a variety of therapeutic applications. Further research is needed to fully understand the role of SCYL1 in cellular processes and its potential as a therapeutic target.

Protein Name: SCY1 Like Pseudokinase 1

Functions: Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652)

More Common Targets

SCYL2 | SDAD1 | SDAD1-AS1 | SDAD1P1 | SDC1 | SDC2 | SDC3 | SDC4 | SDCBP | SDCBP2 | SDCBP2-AS1 | SDCBPP2 | SDCCAG8 | SDE2 | SDF2 | SDF2L1 | SDF4 | SDHA | SDHAF1 | SDHAF2 | SDHAF3 | SDHAF4 | SDHAP1 | SDHAP2 | SDHAP3 | SDHAP4 | SDHB | SDHC | SDHD | SDHDP1 | SDHDP2 | SDK1 | SDK1-AS1 | SDK2 | SDR16C5 | SDR16C6P | SDR39U1 | SDR42E1 | SDR42E2 | SDR9C7 | SDS | SDSL | SEBOX | SEC11A | SEC11B | SEC11C | SEC13 | SEC14L1 | SEC14L1P1 | SEC14L2 | SEC14L3 | SEC14L4 | SEC14L5 | SEC14L6 | SEC16A | SEC16B | SEC1P | SEC22A | SEC22B | SEC22C | SEC23A | SEC23B | SEC23IP | SEC24A | SEC24AP1 | SEC24B | SEC24B-AS1 | SEC24C | SEC24D | SEC31A | SEC31B | SEC61A1 | SEC61A2 | SEC61B | SEC61G | SEC62 | SEC63 | SEC63P2 | SECISBP2 | SECISBP2L | SECTM1 | Segment polarity protein dishevelled homolog | SEH1L | SEL1L | SEL1L2 | SEL1L3 | SELE | SELENBP1 | SELENOF | SELENOH | SELENOI | SELENOK | SELENOKP1 | SELENOM | SELENON | SELENOO | SELENOOLP | SELENOP | Selenoprotein | SELENOS