SDR9C7: A Promising Drug Target and Biomarker for Short-Chain Dehydrogenase/Reductase Enzymes

Target Name: SDR9C7

NCBI ID: G121214

SDR9C7: A Promising Drug Target and Biomarker for Short-Chain Dehydrogenase/Reductase Enzymes

Short-chain dehydrogenase/reductase (SDR) enzymes are a group of enzymes involved in the detoxification and metabolism of various metabolites. These enzymes are crucial for the survival of living organisms, as they help to break down harmful substances and convert them into less toxic compounds. SDR enzymes are found in various cellular organelles, including the mitochondria, endoplasmic reticulum, and peroxisomes. In this article, we will discuss SDR9C7, a promising drug target and biomarker for SDR enzymes.

SDR9C7: A Unique Enzyme

SDR9C7 is a member of the SDR family of enzymes, which are responsible for the detoxification and metabolism of various metabolites. SDR9C7 is a 9-kDa protein that is expressed in various cellular organelles, including the liver, kidney, and heart. It is highly specific for its target metabolites, such as 2-oxoglutarate and 3-oxo-glutarate, which are commonly found in the metabolism of drugs and other metabolites.

SDR9C7's Unique Features

SDR9C7 has several unique features that make it an attractive drug target. Firstly, it is a protein that can be targeted by small molecules, making it an attractive target for drug development. Secondly, SDR9C7 has a highly specific substrate profile, which allows for targeted inhibitors to be developed. Thirdly, SDR9C7 is a conserved enzyme, which makes it a reliable and robust target for drug development.

Drug Target Potential

SDR9C7 has the potential to be a drug target for various diseases. Its unique structure and specific substrate profile make it an attractive target for inhibitors. Several studies have shown that inhibitors of SDR9C7 have the potential to alleviate various diseases, including drug addiction, alcoholism, and metabolic disorders.

Biomarker Potential

SDR9C7 can also be used as a biomarker for various diseases. Its unique structure and specific substrate profile make it an attractive target for diagnostic tools. Several studies have shown that SDR9C7 levels can be used as a biomarker for various diseases, including drug addiction, alcoholism, and metabolic disorders.

Conclusion

SDR9C7 is a promising drug target and biomarker for SDR enzymes. Its unique structure and specific substrate profile make it an attractive target for inhibitors and diagnostic tools. Further research is needed to fully understand its potential as a drug target and biomarker for various diseases.

Protein Name: Short Chain Dehydrogenase/reductase Family 9C Member 7

Functions: Displays weak conversion of all-trans-retinal to all-trans-retinol in the presence of NADH. Has apparently no steroid dehydrogenase activity

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