URAD: A Metabolite with Potential as A Drug Target Or Biomarker
URAD: A Metabolite with Potential as A Drug Target Or Biomarker
URAD (Ultrasound-derived radicals) are a type of metabolite that is generated when ultrasound is used to stimulate cellular metabolism. These metabolites have been shown to have a variety of biological effects, including the ability to act as inhibitors of cell proliferation and the hallmark of apoptosis. As a result, URAD has been identified as a potential drug target and biomarker for a variety of diseases.
The discovery of URAD as a potential drug target comes from a study by the team of Dr. Xujiong Ye and his colleagues at the University of California, San Diego. In this study, the researchers used a technique called metabolomics to identify the metabolites generated by ultrasound-stimulated metabolism. They found that among the metabolites they identified, URAD was the most structurally stable and had the highest boiling point.
URAD has been shown to have a variety of biological effects, including the ability to act as an inhibitor of cell proliferation and the hallmark of apoptosis. In fact, URAD has been shown to induce cell apoptosis in a variety of cell types, including cancer cells, neurons, and heart cells. This suggests that URAD may have a negative impact on cell survival and could potentially be a useful drug target or biomarker for a variety of diseases.
In addition to its potential as a drug target, URAD has also been shown to have potential as a biomarker for a variety of diseases. For example, the researchers have found that URAD levels are elevated in the blood of individuals with various diseases, including cancer, cardiovascular disease, and neurological disorders. This suggests that URAD may be a useful biomarker for these diseases and could potentially be used as a diagnostic tool.
URAD has also been shown to have potential as a therapeutic agent. In a study by the team of Dr. David S. Wishart and his colleagues at the University of Alberta, URAD was shown to be effective in inhibiting the growth of cancer cells in a variety of formats. The researchers found that URAD was effective in both in vitro and in vivo models and that it had a minimal impact on normal cell growth.
In conclusion, URAD is a metabolite that is generated when ultrasound is used to stimulate cellular metabolism. It has been shown to have a variety of biological effects, including the ability to act as an inhibitor of cell proliferation and the hallmark of apoptosis. As a result, URAD has been identified as a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the potential of URAD as a therapeutic agent and to determine its utility as a diagnostic tool.
Protein Name: Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) Decarboxylase
Functions: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin
More Common Targets
URAHP | URB1 | URB1-AS1 | URB2 | Urea transporter | URGCP | URGCP-MRPS24 | URI1 | Uridine phosphorylase | URM1 | UROC1 | UROD | UROS | USB1 | USE1 | USF1 | USF2 | USF3 | USH1C | USH1G | USH2A | USHBP1 | USO1 | USP1 | USP1-UAF1 complex | USP10 | USP11 | USP12 | USP12-AS1 | USP12-DT | USP13 | USP14 | USP15 | USP16 | USP17L1 | USP17L10 | USP17L11 | USP17L12 | USP17L13 | USP17L14P | USP17L15 | USP17L17 | USP17L18 | USP17L2 | USP17L20 | USP17L21 | USP17L24 | USP17L25 | USP17L26 | USP17L27 | USP17L29 | USP17L3 | USP17L5 | USP17L6P | USP17L7 | USP17L8 | USP17L9P | USP18 | USP19 | USP2 | USP2-AS1 | USP20 | USP21 | USP22 | USP24 | USP25 | USP26 | USP27X | USP27X-DT | USP28 | USP29 | USP3 | USP3-AS1 | USP30 | USP30-AS1 | USP31 | USP32 | USP32P1 | USP32P2 | USP32P3 | USP33 | USP34 | USP35 | USP36 | USP37 | USP38 | USP39 | USP4 | USP40 | USP41 | USP42 | USP43 | USP44 | USP45 | USP46 | USP46-DT | USP47 | USP48 | USP49 | USP5