ANKDD1B: A Potential Drug Target and Biomarker (G728780)

Target Name: ANKDD1B

NCBI ID: G728780

Other Name(s): ankyrin repeat and death domain-containing protein ENSP00000345065 | ankyrin repeat and death domain containing 1B | Ankyrin repeat and death domain-containing protein 1B | AKD1B_HUMAN | Ankyrin repeat and death domain containing 1B | Ankyrin repeat and death domain-containing protein ENSP00000345065

ANKDD1B: A Potential Drug Target and Biomarker

Ankyrin repeat and death domain-containing protein (ANKDD1B) is a protein that has been identified as a potential drug target and biomarker. It is a member of the RNA-protein subfamily and is located in the death domain of the protein encoded. ANKDD1B is characterized by a unique structure that consists of an N-terminal ankyrin repeat, a death domain, and a C-terminal T-loop.

The ankyrin repeat is a repetitive nucleotide sequence that is found in various proteins, including RNA-protein hybrids. The death domain is a region of the protein that contains a conserved motif that is involved in the formation of aggregates and is typically involved in the regulation of cell death. The C-terminal T-loop is a conserved structural element that is involved in the regulation of protein stability and localization.

AKNDD1B has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and stress response. It is also involved in the regulation of cell cycle progression and in the development of cancer. Several studies have suggested that ANKDD1B may be a potential drug target due to its unique structure and the involvement in various cellular processes that are related to human disease.

In addition to its potential drug-target potential, ANKDD1B has also been identified as a potential biomarker for various diseases, including cancer. The ankyrin repeat and death domain are conserved across various species, which suggests that they may be useful for the development of biomarkers that are independent of species and can be used to diagnose or monitor disease.

The ankyrin repeat and death domain of ANKDD1B make it an attractive candidate for drug targeting and biomarker development. The N-terminal ankyrin repeat has been shown to interact with various drug targets and has been used as a drug target in various diseases. The death domain is involved in the regulation of cell death and has been shown to play a role in various diseases, including cancer.

In conclusion, ANKDD1B is a protein that has been identified as a potential drug target and biomarker. Its unique structure and the involvement in various cellular processes that are related to human disease make it an attractive candidate for drug targeting and biomarker development. Further research is needed to determine the full potential of ANKDD1B as a drug target and biomarker.

Protein Name: Ankyrin Repeat And Death Domain Containing 1B

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