Target Name: RNF112
NCBI ID: G7732
Other Name(s): BFP | Brain finger protein | Ring finger protein 112 | ZNF179 | Zinc finger protein 179 | ring finger protein 112 | brain finger protein | zinc finger protein 179 | RING finger protein 112 | RN112_HUMAN | neurolastin

Exploring The Biology of RFP112: A Potential Drug Target Or Biomarker for Various Diseases

RNA-Foldable Proteins (RFPs) are a family of proteins that play a crucial role in various cellular processes. One of the subfamilies of RFPs, named RFP112 (BFP), has been identified as a potential drug target or biomarker for various diseases. This This article will explore the biology of RFP112, its potential as a drug target, and its potential as a biomarker for disease.

The RNA-Foldable Proteins (RFPs) are a family of proteins that can self-assemble into well-defined structures with a high degree of accuracy. These proteins are involved in various cellular processes, including cell signaling, DNA replication, and protein degradation. The subfamily of RFPs named RFP112 (BFP) is a member of this family.

RFP112 is a 25 kDa protein that is expressed in various tissues and cells, including brain, heart, liver, and muscle. It is composed of a unique protein domain that consists of a 尾-sheet and a 10-amino acid loop. This protein domain is responsible for the protein's stability and stability-related functions.

RFP112 has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and protein degradation. For example, studies have shown that RFP112 can interact with various protein partners, including casein kinase 2 (CK-2), a protein that is involved in protein-protein interactions and cell signaling.

Additionally, RFP112 has been shown to be involved in DNA replication. During DNA replication, RFP112 has been shown to interact with the protein Pluto(Thr128), which is involved in the initiation of DNA replication. This interaction between RFP112 and Thr128 suggests that RFP112 may play a role in regulating DNA replication.

Another study has shown that RFP112 is involved in protein degradation. Studies have shown that RFP112 can interact with the protein parkin, which is involved in protein degradation. This interaction between RFP112 and Parkin suggests that RFP112 may play a role in regulating protein degradation.

Potential Drug Target

RFP112's involvement in various cellular processes makes it a potential drug target or biomarker. The high degree of accuracy with which RFP112 can self-assemble into well-defined structures makes it an attractive candidate for drug targeting.

One of the potential drug targets for RFP112 is the protein casein kinase 2 (CK-2). CK-2 is a protein that is involved in protein-protein interactions and cell signaling. Studies have shown that RFP112 can interact with CK-2, which suggests that RFP112 may play a role in regulating CK-2 signaling.

Another potential drug target for RFP112 is the protein p16INK4a. p16INK4a is a protein that is involved in cell signaling and has been implicated in various diseases, including cancer. Studies have shown that RFP112 can interact with p16INK4a, which suggests that RFP112 may play a role in regulating p16INK4a signaling.

Potential Biomarkers

RFP112 may also be used as a biomarker for various diseases. The high degree of accuracy with which RFP112 can self-assemble into well-defined structures makes it an attractive candidate for biomarker development.

One of the potential biomarkers for RFP112 is its ability to interact with protein partners, such as casein kinase 2 (CK-2) and p16INK4a. These protein partners are involved in various cellular processes and have been implicated in various diseases, including cancer. By targeting these protein partners, RFP112 may be able

Protein Name: Ring Finger Protein 112

Functions: E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins (PubMed:28684796). Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage. Exhibits GTPase and E3 ubiquitin-protein ligase activities. Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density (By similarity)

More Common Targets

RNF113A | RNF113B | RNF114 | RNF115 | RNF121 | RNF122 | RNF123 | RNF125 | RNF126 | RNF126P1 | RNF128 | RNF13 | RNF130 | RNF133 | RNF135 | RNF138 | RNF138P1 | RNF139 | RNF139-DT | RNF14 | RNF141 | RNF144A | RNF144B | RNF145 | RNF146 | RNF148 | RNF149 | RNF150 | RNF151 | RNF152 | RNF157 | RNF157-AS1 | RNF165 | RNF166 | RNF167 | RNF168 | RNF169 | RNF17 | RNF170 | RNF175 | RNF180 | RNF181 | RNF182 | RNF183 | RNF185 | RNF186 | RNF187 | RNF19A | RNF19B | RNF2 | RNF20 | RNF207 | RNF208 | RNF212 | RNF212B | RNF213 | RNF213-AS1 | RNF214 | RNF215 | RNF216 | RNF216-IT1 | RNF216P1 | RNF217 | RNF217-AS1 | RNF220 | RNF222 | RNF224 | RNF225 | RNF227 | RNF24 | RNF25 | RNF26 | RNF31 | RNF32 | RNF32-DT | RNF34 | RNF38 | RNF39 | RNF4 | RNF40 | RNF41 | RNF43 | RNF44 | RNF5 | RNF5P1 | RNF6 | RNF7 | RNF7P1 | RNF8 | RNFT1 | RNFT2 | RNGTT | RNH1 | RNLS | RNMT | RNPC3 | RNPC3-DT | RNPEP | RNPEPL1 | RNPS1