KIF23: A Protein Critical for Cell Signaling and Movement (G9493)
KIF23: A Protein Critical for Cell Signaling and Movement
Kinesin Family Member 23 (KIF23) is a protein that plays a critical role in the proper functioning of cells. It is a member of the kinesin family, which is known for their ability to transport proteins across cell membranes. KIF23 is expressed in many different tissues and cells throughout the body, including muscle, nerve, and brain cells.
One of the key functions of KIF23 is its role in cell signaling. It is involved in the regulation of several different signaling pathways, including the TGF-β pathway and the Wnt pathway. TGF-β is a well-known growth factor that regulates cell growth, while the Wnt pathway is involved in the development and maintenance of tissues, including muscles and bones.
KIF23 is also involved in the regulation of cell adhesion. It helps to keep cells connected to each other and to the surrounding tissue, which is important for the development and maintenance of tissues and organs.
In addition to its role in cell signaling and adhesion, KIF23 is also involved in the regulation of cell movement. It helps to control the movement of cells in the direction that they want to move, which is important for the proper functioning of tissues and organs.
KIF23 is also a potential drug target. Researchers are studying its potential as a treatment for a variety of different conditions, including cancer, neurodegenerative diseases, and developmental disorders.
One of the main reasons for the potential of KIF23 as a drug target is its ability to interact with a variety of different proteins. It has been shown to interact with several different proteins, including the protein known as PDGF-BB. This protein is involved in cell signaling and is a key regulator of cell growth and differentiation.
Research has also shown that KIF23 can interact with the protein known as TGF-β2. This protein is involved in the regulation of cell growth and is a key regulator of tissue development and maintenance.
In addition to its interactions with PDGF-BB and TGF-β2, KIF23 has also been shown to interact with several other proteins. These include the protein known as FAK, which is involved in cell adhesion and the protein known as NF-kappa-B, which is involved in cell signaling.
KIF23 is also a potential biomarker for several different diseases. For example, it has been shown to be involved in the development of cancer. Additionally, KIF23 has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
In conclusion, KIF23 is a protein that plays a critical role in the proper functioning of cells. It is a member of the kinesin family and is involved in the regulation of several different signaling pathways, including the TGF-β pathway and the Wnt pathway. KIF23 is also involved in the regulation of cell adhesion and movement, and has been shown to be a potential drug target and biomarker for several different diseases. Further research is needed to fully understand its functions and potential uses.
Protein Name: Kinesin Family Member 23
Functions: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro
More Common Targets
KIF23-AS1 | KIF24 | KIF25 | KIF25-AS1 | KIF26A | KIF26B | KIF27 | KIF28P | KIF2A | KIF2B | KIF2C | KIF3A | KIF3B | KIF3C | KIF4A | KIF4B | KIF5A | KIF5B | KIF5C | KIF6 | KIF7 | KIF9 | KIF9-AS1 | KIFAP3 | KIFBP | KIFC1 | KIFC2 | KIFC3 | Killer Cell Immunoglobulin-Like Receptor (KIR) | Killer cell immunoglobulin-like receptor 2DS1, transcript variant X1 | KIN | Kinesin-like protein KIF16B (isoform 1) | KIR2DL1 | KIR2DL2 | KIR2DL3 | KIR2DL4 | KIR2DL5A | KIR2DL5B | KIR2DP1 | KIR2DS1 | KIR2DS2 | KIR2DS3 | KIR2DS4 | KIR2DS5 | KIR3DL1 | KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4 | KLHDC7A | KLHDC7B | KLHDC7B-DT | KLHDC8A | KLHDC8B | KLHDC9 | KLHL1 | KLHL10