Exploring the Potential Drug Target or Biomarker CEP170 (CEP170 Variant Beta)
Exploring the Potential Drug Target or Biomarker CEP170 (CEP170 Variant Beta)
Abstract:
CEP170 (CEP170 variant beta) is a protein that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. This protein plays a crucial role in the immune response and has been linked to various diseases diseases. In this article, we will discuss the research on CEP170, its potential drug target status, and its potential as a biomarker for various diseases.
Introduction:
CEP170 (CEP170 variant beta) is a protein that is expressed in various tissues and cells of the body. It is a member of the immunoglobulin superfamily (Ig superfamily) and has been implicated in the immune response, inflammation, and neurodegenerative disorders. Several studies have suggested that CEP170 may have potential as a drug target or biomarker for various diseases. In this article, we will explore the research on CEP170, its potential drug target status, and its potential as a biomarker for various diseases.
Potential Drug Target Status:
CEP170 has been identified as a potential drug target due to its unique structure and its involvement in various signaling pathways. CEP170 is a glycoprotein that consists of two heavy chains and two light chains. It has a unique N-terminal region that contains a glycine loop and a potential N-glycosylation site. This region is known as the N-glycosylation site (N-GSSG) and has been implicated in various signaling pathways.
One of the potential drug targets for CEP170 is its N-GSSG site. Studies have shown that N-GSSG sites are often targeted by small molecules, including drugs, toxins, and other substances that can modulate the activity of proteins. The N-GSSG site on CEP170 has been shown to be a potential drug target by various methods, including biochemical assays, cellular assays, and structural studies.
In addition to its N-GSSG site, CEP170 has also been shown to have a potential drug target in its Fc region. The Fc region is a region of the protein that contains various carbohydrates and is known for its role in complementation and immune response. Studies have shown that the Fc region of CEP170 contains a conserved region that is involved in the interaction with other proteins, including antibodies. This region has been implicated in various signaling pathways and may be a potential drug target.
Potential Biomarker Status:
CEP170 has also been suggested as a potential biomarker for various diseases due to its unique expression pattern and its involvement in various signaling pathways. Changes in the expression of CEP170 have been observed in various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.
Studies have shown that changes in CEP170 expression levels can be associated with the development and progression of various diseases. For example, studies have shown that high expression of CEP170 is associated with poor prognosis in neurodegenerative disorders, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. Similarly, changes in CEP170 expression levels have been observed in various types of cancer, including breast cancer, lung cancer, and colorectal cancer.
In addition to its association with diseases, CEP170 has also been shown to be a potential biomarker for certain diseases. For example, studies have shown that changes in CEP170 expression levels can be associated with the severity of autoimmune diseases, such as rheumatoid arthritis, lupus , and multiple sclerosis.
Conclusion:
In conclusion, CEP170 (CEP170 variant beta) is a protein that has been identified as a potential drug target or biomarker for various diseases. Its unique structure and involvement in various signaling pathways make it an attractive target for small molecules. Further research is needed to
Protein Name: Centrosomal Protein 170
Functions: Plays a role in microtubule organization (PubMed:15616186). Required for centriole subdistal appendage assembly (PubMed:28422092)
More Common Targets
CEP170B | CEP170P1 | CEP19 | CEP192 | CEP20 | CEP250 | CEP290 | CEP295 | CEP295NL | CEP350 | CEP350-FGFR1OP-MAPRE1 complex | CEP41 | CEP43 | CEP44 | CEP55 | CEP57 | CEP57L1 | CEP63 | CEP68 | CEP70 | CEP72 | CEP72-DT | CEP76 | CEP78 | CEP83 | CEP83-DT | CEP85 | CEP85L | CEP89 | CEP95 | CEP97 | CEPT1 | CER1 | Ceramidase | Ceramide synthase | CERCAM | CERK | CERKL | CERNA2 | CERS1 | CERS2 | CERS3 | CERS3-AS1 | CERS4 | CERS5 | CERS6 | CERS6-AS1 | CERT1 | CES1 | CES1P1 | CES1P2 | CES2 | CES3 | CES4A | CES5A | CETN1 | CETN2 | CETN3 | CETN4P | CETP | CFAP100 | CFAP100-DT | CFAP107 | CFAP119 | CFAP126 | CFAP141 | CFAP157 | CFAP161 | CFAP20 | CFAP206 | CFAP20DC | CFAP20DC-AS1 | CFAP20DC-DT | CFAP210 | CFAP221 | CFAP251 | CFAP276 | CFAP298 | CFAP299 | CFAP300 | CFAP36 | CFAP410 | CFAP418 | CFAP418-AS1 | CFAP43 | CFAP44 | CFAP44-AS1 | CFAP45 | CFAP46 | CFAP47 | CFAP52 | CFAP53 | CFAP54 | CFAP57 | CFAP58 | CFAP61 | CFAP65 | CFAP68 | CFAP69 | CFAP70