Understanding RRAGA: A Protein Regulator of the Immune Response

Target Name: RRAGA

NCBI ID: G10670

Understanding RRAGA: A Protein Regulator of the Immune Response

RRAGA, short for Responsiveness to Antigens, is a protein that is expressed in many different tissues in the body. It is a key regulator of the immune response, and has been shown to play a role in a variety of diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. As a drug target or biomarker, RRAGA has the potential to be a valuable tool for the development of new treatments for these diseases.

RRAGA was first identified in the 1990s as a key regulator of T cell development and function. Since then, it has been shown to play a role in a variety of immune processes, including the regulation of dendritic cell development, the generation of T cells, and the regulation of inflammation. In addition, RRAGA has also been shown to play a role in the development and progression of cancer, as well as in the development of autoimmune disorders such as rheumatoid arthritis and multiple sclerosis.

RRAGA is a protein that is expressed in many different tissues in the body, including the brain, spinal cord, heart, kidneys, and gastrointestinal tract. It is a key regulator of the immune response, and is involved in the development and regulation of T cells, B cells, and natural killer cells. In addition, RRAGA is also involved in the regulation of inflammation, and has been shown to play a role in the development of a variety of diseases, including cancer, autoimmune disorders, and neurodegenerative diseases.

One of the key functions of RRAGA is its ability to respond to the presence of foreign substances in the body. This is accomplished through the regulation of the immune response, which is a critical part of the body's ability to defend against infection and disease.RRAGA plays a key role in this process by regulating the activation and proliferation of T cells, which are a critical part of the immune system.

In addition, RRAGA is also involved in the regulation of the development and function of dendritic cells, which are a type of immune cell that play a critical role in the generation of T cells. Dendritic cells are responsible for presenting foreign substances to T cells, and for helping to stimulate an immune response.RRAGA plays a key role in this process by regulating the development and function of dendritic cells, and by ensuring that they are able to effectively present foreign substances to T cells.

RRAGA is also involved in the regulation of inflammation, and has been shown to play a role in the development of a variety of diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. In addition, RRAGA is also involved in the regulation of the development and function of natural killer cells, which are a type of immune cell that play a critical role in the immune response.

In conclusion, RRAGA is a protein that is expressed in many different tissues in the body and plays a key role in the immune response. As a drug target or biomarker, RRAGA has the potential to be a valuable tool for the development of new treatments for a variety of diseases. Further research is needed to fully understand the role of RRAGA in the immune response and its potential as a drug target or biomarker.

Protein Name: Ras Related GTP Binding A

Functions: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade (PubMed:20381137, PubMed:24095279, PubMed:25936802). Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form (PubMed:20381137, PubMed:24095279, PubMed:25936802, PubMed:32868926). In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB (PubMed:20381137, PubMed:25936802). Involved in the RCC1/Ran-GTPase pathway (PubMed:9394008). May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death (PubMed:8995684)

More Common Targets