Target Name: IMMT
NCBI ID: G10989
Other Name(s): P89 | PIG4 | cell proliferation-inducing gene 4/52 protein | Cell proliferation-inducing protein 52 | IMMT variant 1 | Mitofilin | proliferation-inducing gene 4 | Mic60 | Proliferation-inducing gene 4 | mitochondrial inner membrane organizing system 2 | motor protein | heart muscle protein | P87 | Motor protein | PIG52 | inner membrane mitochondrial protein | MINOS2 | Mitochondrial inner membrane protein | Cell proliferation-inducing gene 4/52 protein | mitofilin | MICOS complex subunit MIC60 (isoform 1) | Mitochondrial inner membrane organizing system 2 | Inner membrane mitochondrial protein, transcript variant 1 | HMP | mitochondrial inner membrane protein | P87/89 | MICOS60 | mitochondrial contact site and cristae organizing system subunit 60 | p87/89 | cell proliferation-inducing protein 52 | MICOS complex subunit MIC60 | MIC60_HUMAN

IMMT: A Drug Target and Biomarker for Treating Various Diseases

IMMT (Immunomodulatory target molecule) is a drug target and a biomarker that is being studied for its potential role in treating various diseases. IMMT is a protein that is expressed in various tissues throughout the body, including the immune system, and has been shown to play a role in the regulation of immune responses and inflammation.

One of the main functions of IMMT is its role in the regulation of T cell responses. T cells are a type of immune cell that play a critical role in the immune system by helping to fight off infections and diseases. IMMT has been shown to help regulate the activity of T cells, which is important for maintaining a healthy immune system.

In addition to its role in T cell regulation, IMMT has also been shown to play a role in the regulation of inflammation. Inflammation is a natural response of the immune system, but when it becomes chronic or uncontrolled, it can lead to a range of diseases, including chronic pain, autoimmune diseases, and even cancer. IMMT has been shown to help regulate the activity of immune cells that contribute to inflammation, which may have implications for the treatment of these diseases.

Another potential use for IMMT as a drug target is its role in the regulation of cancer cell growth. Many cancer cells are able to evade the immune system's defenses and continue to grow and multiply. IMMT has been shown to help regulate the activity of cancer cells, which may have implications for the development of new cancer treatments.

IMMT has also been shown to have potential as a biomarker for certain diseases. For example, IMMT has been shown to be elevated in the blood of people with rheumatoid arthritis, a type of autoimmune disease. This suggests that IMMT may be a useful biomarker for the diagnosis and monitoring of this disease.

In conclusion, IMMT is a drug target and biomarker that has the potential to treat a wide range of diseases. Further research is needed to fully understand its role and potential as a new drug or biomarker.

Protein Name: Inner Membrane Mitochondrial Protein

Functions: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180)

More Common Targets

IMMTP1 | Immunoglobulin A | Immunoglobulin E (IgE) | Immunoglobulin G | Immunoglobulin M | Immunoglobulin-Like Domain Containing Receptor | Immunoproteasome | IMP3 | IMP4 | IMPA1 | IMPA1P1 | IMPA2 | IMPACT | IMPDH1 | IMPDH1P10 | IMPDH1P6 | IMPDH2 | IMPG1 | IMPG2 | INA | INAFM1 | INAFM2 | INAVA | INCA1 | INCENP | INE1 | INE2 | INF2 | ING1 | ING2 | ING2-DT | ING3 | ING4 | ING5 | INGX | INHA | INHBA | INHBA-AS1 | INHBB | INHBC | INHBE | INHCAP | Inhibitor of Apoptosis Proteins (IAPs) | Inhibitory kappaB Kinase (IKK) | INIP | INKA1 | INKA2 | INKA2-AS1 | INMT | INMT-MINDY4 | Innate Repair Receptor (IRR) | INO80 | INO80 complex | INO80B | INO80B-WBP1 | INO80C | INO80D | INO80E | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) | Inositol hexakisphosphate kinase | Inositol Monophosphatase | INPP1 | INPP4A | INPP4B | INPP5A | INPP5B | INPP5D | INPP5E | INPP5F | INPP5J | INPP5K | INPPL1 | INS | INS-IGF2 | INSC | INSIG1 | INSIG2 | INSL3 | INSL4 | INSL5 | INSL6 | INSM1 | INSM2 | INSR | INSRR | Insulin-like growth factor | Insulin-like growth factor 2 mRNA binding protein | Insulin-like growth factor 2 mRNA-binding protein 1 (isoform 2) | Insulin-like growth factor-binding protein | INSYN1 | INSYN2A | INSYN2B | Integrator complex | Integrin alpha1beta1 (VLA-1) receptor | Integrin alpha2beta1 (VLA-2) receptor | Integrin alpha2beta3 Receptor | Integrin alpha3beta1 receptor | Integrin alpha4beta1 (VLA-4) receptor | Integrin alpha4beta7 (LPAM-1) receptor | Integrin alpha5beta1 (VLA-5) receptor