EIF4B: A Drug Target / Disease Biomarker (G1975)

Target Name: EIF4B

NCBI ID: G1975

EIF4B: A Drug Target / Disease Biomarker

EIF4B, also known as EIF4B-ASF, is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the EIF4B family, which is known for its role in the regulation of cellular signaling pathways. One of the EIF4B proteins, EIF4B-ASF, has been identified as a potential drug target or biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The EIF4B family is involved in the regulation of several cellular signaling pathways that are critical for cell survival and function. One of the key functions of the EIF4B family is the regulation of the JAK/STAT signaling pathway. This pathway is involved in the regulation of cell proliferation, differentiation, and survival, and is a key factor in the development and progression of many diseases.

EIF4B-ASF, a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract, is a member of the EIF4B family and plays a role in the regulation of the JAK/STAT signaling pathway.

One of the key functions of the EIF4B family is the regulation of the JAK/STAT signaling pathway. This pathway is involved in the regulation of cell proliferation, differentiation, and survival, and is a key factor in the development and progression of many diseases. EIF4B-ASF is a key component of this pathway, as it has been shown to play a role in the regulation of STAT3, a protein that is involved in the JAK/STAT signaling pathway.

Studies have shown that EIF4B-ASF is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract, and is involved in the regulation of cellular signaling pathways that are critical for cell survival and function. This suggests that EIF4B-ASF may be a potential drug target or biomarker for a variety of diseases.

In addition to its role in the JAK/STAT signaling pathway, EIF4B-ASF has also been shown to play a role in the regulation of other signaling pathways that are important for cell survival and function. For example, EIF4B-ASF has been shown to play a role in the regulation of the PI3K/AKT signaling pathway, a pathway that is involved in the regulation of cell survival and metabolism.

EIF4B-ASF has also been shown to play a role in the regulation of the NF-kappa-B signaling pathway, a pathway that is involved in the regulation of inflammation and immune responses. This suggests that EIF4B-ASF may be a potential drug target or biomarker for diseases that are characterized by inflammation or immune dysfunction.

In conclusion, EIF4B-ASF is a protein that is expressed in various tissues of the body and plays a role in the regulation of several cellular signaling pathways that are critical for cell survival and function. The potential drug target or biomarker status of EIF4B-ASF makes it a promising target for the development of new treatments for a variety of diseases. Further research is needed to fully understand the role of EIF4B-ASF in cellular signaling pathways and its potential as a drug target or biomarker.

Protein Name: Eukaryotic Translation Initiation Factor 4B

Functions: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F

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