EML1: The Potential Drug Target and Biomarker (G2009)

Target Name: EML1

NCBI ID: G2009

EML1: The Potential Drug Target and Biomarker

EML1 (EMAP-1), also known as EML1-TK, is a protein that is expressed in various tissues of the human body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the EMAP family, which includes EMAP1, EMAP2, and EMAP3, and is characterized by the presence of a unique N-terminal transmembrane domain and a C-terminal protein domain.

EML1 has been identified as a potential drug target due to its unique structure and the various functions that it has been shown to play in various physiological processes. One of the key functions of EML1 is its role in the regulation of cell adhesion, which is critical for the development and maintenance of tissues and organs.

EML1 has been shown to play a key role in the regulation of neuronal cell adhesion, which is the process by which cells stick together to form tissues and organs. In addition, EML1 has been shown to regulate the formation of tight junctions, which are the specialized structures that allow cells to communicate with one another and to form tissues.

EML1 has also been shown to play a role in the regulation of stem cell proliferation and the differentiation of stem cells into different cell types. In addition, EML1 has been shown to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed.

In addition to its role in cell adhesion and angiogenesis, EML1 has also been shown to play a key role in the regulation of inflammation. In addition, EML1 has been shown to play a role in the regulation of the immune response, which is critical for the defense against infection and disease.

EML1 has also been shown to play a role in the regulation of metabolism and the regulation of cellular signaling pathways. In addition, EML1 has been shown to play a role in the regulation of the DNA damage response, which is critical for the regulation of gene expression and the maintenance of cellular health.

In conclusion, EML1 is a protein that has been shown to play a key role in a variety of physiological processes, including the regulation of cell adhesion, neuronal cell adhesion, stem cell proliferation and differentiation, angiogenesis, inflammation, and metabolism. As a result, EML1 has the potential to be a drug target for a variety of therapeutic applications. Further research is needed to fully understand the functions of EML1 and to develop safe and effective treatments for the treatment of diseases associated with its dysfunction.

Protein Name: EMAP Like 1

Functions: Modulates the assembly and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain development. Does not affect neuron migration per se

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