FSHB: A Protein with Potential for Drug Targeting and Biomarker

Target Name: FSHB

NCBI ID: G2488

FSHB: A Protein with Potential for Drug Targeting and Biomarker

FSHB (FSHB variant 1) is a protein that is expressed in the heart and is known for its role in cardiac function. It is a key regulator of cardiac muscle contractions and has been implicated in a number of cardiovascular diseases, including heart failure, arrhythmia , and sudden cardiac death.

In recent years, researchers have been interested in studying FSHB as a potential drug target or biomarker for a number of reasons. One of the main reasons is that FSHB is a strong candidate for a drug target because it is involved in a number of important physiological processes in the body. For example, FSHB is involved in regulating the heart rate and contractions, which are critical for maintaining blood flow to the body's tissues. It is also involved in regulating the electrical activity of the heart, which is important for maintaining a normal heart rhythm.

In addition to its role in cardiovascular function, FSHB is also a good candidate for a drug target because it is involved in a number of signaling pathways that are important for the development and progression of many diseases. For example, FSHB is involved in the FGF signaling pathway, which is important for the development of tissues and organs, as well as the regulation of cell proliferation and differentiation. It is also involved in the TGF-β signaling pathway, which is important for the regulation of cell growth and differentiation, as well as the regulation of the immune response.

FSSHB is also a good candidate for a drug target because it is a protein that is expressed in many different tissues and organs, which makes it a potential biomarker for a variety of diseases. For example, FSHB is expressed in the heart, brain, and pancreas, which makes it a potential biomarker for a variety of cardiovascular and neurological diseases. It is also expressed in other tissues and organs, such as the lungs, liver, and bone, which could make it a potential biomarker for a variety of other diseases..

In conclusion, FSHB is a protein that is involved in a number of important physiological processes in the body and is a good candidate for a drug target or biomarker. Its involvement in the FGF and TGF-β signaling pathways, as well as its expression in a variety of tissues and organs, makes it a promising candidate for a variety of potential therapeutic applications. Further research is needed to fully understand the role of FSHB in the development and progression of cardiovascular and other diseases.

Protein Name: Follicle Stimulating Hormone Subunit Beta

Functions: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:2494176, PubMed:24692546). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432)

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