G2E3: Key Player in Ubiquitin System (G55632)

Target Name: G2E3

NCBI ID: G55632

G2E3: Key Player in Ubiquitin System

G2E3 (G2/M-phase specific E3 ubiquitin protein ligase, transcript variant 1) is a protein that is expressed in various tissues and cells throughout the body. It is a key player in the ubiquitin system, a protein-protein interaction network that plays a crucial role in various cellular processes, including cell signaling, DNA damage repair, and inflammation. G2E3 is also known as E3 ubiquitin protein ligase, transcript variant 1.

G2E3 is a 21-kDa protein that consists of 21 amino acid residues. It belongs to the E3 ubiquitin family, which is characterized by the presence of a characteristic Rossmann-fold in the protein sequence. This family plays a central role in the regulation of various cellular processes, including DNA damage repair, cell signaling, and inflammation.

G2E3 is expressed in various tissues and cells throughout the body, including the liver, lung, heart, kidney, and pancreas. It is also expressed in the placenta, which supports the development and maintenance of fetal tissues. G2E3 is involved in the ubiquitin system, which is a protein-protein interaction network that plays a crucial role in various cellular processes.

G2E3 is involved in the regulation of various cellular processes, including cell signaling, DNA damage repair, and inflammation. It is a key player in the ubiquitin system, which is a protein-protein interaction network that plays a crucial role in

Protein Name: G2/M-phase Specific E3 Ubiquitin Protein Ligase

Functions: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death

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