Target Name: FTH1P3
NCBI ID: G2498
Other Name(s): FTHL3P | FTHL3 | Ferritin heavy chain 1 pseudogene 3 | ferritin heavy chain 1 pseudogene 3

FTH1P3: A Potential Drug Target and Biomarker

FTH1P3, also known as FTHL3P, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Fth1 family of transmembrane proteins, which are involved in the regulation of ion and water transport across cell membranes. FTH1P3 has been identified as a potential drug target due to its unique structure and its involvement in several physiological processes.

The Fth1 family of proteins consists of four isoforms: FTH1P1, FTH1P2, FTH1P3, and FTH1P4. These isoforms differ in their N-terminus, and FTH1P3 is the most abundant isoform in the brain and nervous system. It is expressed in the brain and retina, and has been shown to play a role in the regulation of neuronal excitability and synaptic plasticity.

One of the key functions of FTH1P3 is its role in the regulation of intracellular ion levels. FTH1P3 is involved in the uptake and release of ions in the brain, includingNa+,K+, andCa2+. It does this by playing a role in the regulation of the ion channels that control the flow of these ions into and out of cells.

FTH1P3 is also involved in the regulation of water transport across cell membranes. It is a member of the family of TRPV4-containing channels, which are involved in the regulation of pain perception and the sensation of touch. These channels play a crucial role in the perception of pain and discomfort, and are thought to be involved in the development of certain neurological disorders.

In addition to its role in ion and water transport, FTH1P3 is also involved in the regulation of cell adhesion and migration. It is a member of the Focal Adhesion Protein (FAX) family, which is involved in the regulation of cell-cell adhesion and the migration of cells. FTH1P3 plays a role in the regulation of FAX-4, a protein that is involved in the regulation of cell adhesion and migration.

FTH1P3 is also involved in the regulation of cellular signaling pathways. It is a member of the PIP4K2A complex, which is involved in the regulation of several cellular signaling pathways, including the regulation of cell growth, differentiation, and survival.

Given its involvement in a wide range of physiological processes, FTH1P3 is a promising drug target. Studies have shown that inhibiting the activity of FTH1P3 can have a variety of therapeutic effects, including the inhibition of pain perception and the regulation of cell migration. Additionally, FTH1P3 has been shown to play a role in the regulation of neuronal excitability and synaptic plasticity, making it a potential target for the treatment of neurological disorders.

In conclusion, FTH1P3 is a protein that is involved in a wide range of physiological processes in the body. Its unique structure and its involvement in several regulatory processes make it a promising drug target. Further research is needed to fully understand the role of FTH1P3 in the regulation of cellular processes and to develop effective treatments for the prevention and treatment of disorders that are related to its dysfunction.

Protein Name: Ferritin Heavy Chain 1 Pseudogene 3

More Common Targets

FTH1P4 | FTH1P5 | FTH1P7 | FTH1P8 | FTHL17 | FTL | FTLP16 | FTLP2 | FTLP3 | FTLP7 | FTMT | FTO | FTO-IT1 | FTOP1 | FTSJ1 | FTSJ3 | FTX | FUBP1 | FUBP3 | FUCA1 | FUCA2 | Fucosyl GM1 | Fucosyltransferase | FUNDC1 | FUNDC2 | FUNDC2P2 | FUNDC2P3 | FUOM | FURIN | FUS | FUT1 | FUT10 | FUT11 | FUT2 | FUT3 | FUT4 | FUT5 | FUT6 | FUT7 | FUT8 | FUT8-AS1 | FUT9 | FUZ | FXN | FXR1 | FXR2 | FXYD1 | FXYD2 | FXYD3 | FXYD4 | FXYD5 | FXYD6 | FXYD6-FXYD2 | FXYD7 | FYB1 | FYB2 | FYCO1 | FYN | FYTTD1 | FZD1 | FZD10 | FZD10-AS1 | FZD2 | FZD3 | FZD4 | FZD4-DT | FZD5 | FZD6 | FZD7 | FZD8 | FZD9 | FZR1 | G protein-Coupled Inwardly-Rectifying Potassium Channel (GIRK) | G Protein-Coupled Receptor Kinases (GRKs) | G0S2 | G2E3 | G2E3-AS1 | G3BP1 | G3BP2 | G6PC1 | G6PC2 | G6PC3 | G6PD | GA-binding protein | GAA | GAB1 | GAB2 | GAB3 | GAB4 | GABA(A) receptor | GABARAP | GABARAPL1 | GABARAPL2 | GABARAPL3 | GABBR1 | GABBR2 | GABPA | GABPAP | GABPB1 | GABPB1-AS1