Target Name: DPH5
NCBI ID: G51611
Other Name(s): AD-018 | Diphthine methyl ester synthase (isoform a) | Diphthamide biosynthesis 5, transcript variant 2 | DPH5 variant 1 | Diphthamide biosynthesis methyltransferase | CGI-30 | DPH5 variant 2 | NPD015 | DPH5 homolog | diphthamide biosynthesis 5 | S-adenosyl-L-methionine:elongation factor 2 methyltransferase | NEDSFF | HSPC143 | Diphthine methyltransferase | Diphthine methyl ester synthase | DPH5_HUMAN | diphthamide biosynthesis methyltransferase | Protein x 0011 | protein x 0011 | diphthine synthase | Diphthamide biosynthesis 5, transcript variant 1

DPH5: A Protein Involved in Cellular Movement, Gene Expression, Cytoskeleton and Signaling

DPH5 (AD-018) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of cytoskeletal proteins, which are involved in the structure and function of cells. DPH5 is unique among these proteins because it is able to interact with a variety of different molecules, including transcription factors, hormones, and neurotransmitters. This interactivity makes DPH5 an attractive target for research into a variety of biological processes, including neurodegenerative diseases, image processing, and drug development.

One of the key functions of DPH5 is its role in the regulation of cellular movement. DPH5 is involved in the formation of microtubules, which are the structural elements that give cells their characteristic shape and help them to move and function. In addition, DPH5 is involved in the regulation of the speed at which cells move, which is important for processes such as cell division, migration, and intracellular transport.

Another important function of DPH5 is its role in the regulation of gene expression. DPH5 is able to interact with a variety of different transcription factors, which are proteins that help to turn on or off the genes that are present in a cell. This interaction between DPH5 and transcription factors allows DPH5 to play a role in the regulation of cellular processes such as cell growth, differentiation, and inflammation.

In addition to its role in the regulation of cellular movement and gene expression, DPH5 is also involved in the regulation of the structure and function of cells. DPH5 is a protein that is involved in the formation of the cytoskeleton, which is the structure that gives cells their shape and helps them to maintain their integrity. In addition, DPH5 is involved in the regulation of the stability of the cytoskeleton, which is important for the proper functioning of cells.

DPH5 is also involved in the regulation of cellular signaling processes. DPH5 is able to interact with a variety of different signaling molecules, including hormones and neurotransmitters. This interaction between DPH5 and signaling molecules allows DPH5 to play a role in the regulation of cellular processes such as cell growth, differentiation, and signaling.

In conclusion, DPH5 is a protein that is involved in a variety of important cellular processes. Its unique ability to interact with a variety of different molecules makes DPH5 an attractive target for research into a wide range of biological phenomena. While further research is needed to fully understand the role of DPH5 in the regulation of cellular processes, its potential as a drug target is an exciting area of study.

Protein Name: Diphthamide Biosynthesis 5

Functions: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis

More Common Targets

DPH5-DT | DPH6 | DPH6-DT | DPH7 | DPM1 | DPM2 | DPM3 | DPP10 | DPP10-AS1 | DPP3 | DPP3-DT | DPP4 | DPP6 | DPP7 | DPP8 | DPP9 | DPP9-AS1 | DPPA2 | DPPA2P3 | DPPA3 | DPPA3P1 | DPPA3P2 | DPPA4 | DPPA4P3 | DPPA5 | DPPA5P4 | DPRX | DPRXP2 | DPRXP4 | DPT | DPY19L1 | DPY19L1P1 | DPY19L2 | DPY19L2P1 | DPY19L2P2 | DPY19L2P3 | DPY19L2P4 | DPY19L3 | DPY19L3-DT | DPY19L4 | DPY30 | DPYD | DPYD-AS1 | DPYS | DPYSL2 | DPYSL3 | DPYSL4 | DPYSL5 | DQX1 | DR1 | DRAIC | DRAM1 | DRAM2 | DRAP1 | DRAXIN | DRB sensitivity-inducing factor complex | DRC1 | DRC3 | DRC7 | DRD1 | DRD2 | DRD3 | DRD4 | DRD5 | DRD5P1 | DRD5P2 | DRG1 | DRG2 | DRGX | DRICH1 | DROSHA | DRP2 | DSC1 | DSC2 | DSC3 | DSCAM | DSCAM-AS1 | DSCAML1 | DSCC1 | DSCR10 | DSCR4 | DSCR8 | DSCR9 | DSE | DSEL | DSEL-AS1 | DSG1 | DSG1-AS1 | DSG2 | DSG3 | DSG4 | DSN1 | DSP | DSP-AS1 | DSPP | DST | DST-AS1 | DSTN | DSTNP2 | DSTYK