THSD1: Negative Regulator of PD-L1 Signaling Pathway (G55901)

Target Name: THSD1

NCBI ID: G55901

THSD1: Negative Regulator of PD-L1 Signaling Pathway

THSD1 (Unq3010) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the superfamily of protein tyrosine kinase (PTK), which is a family of enzymes that regulate protein tyrosine phosphorylation (PT) in response to extracellular signals.

THSD1 is known for its role in the regulation of cellular signaling pathways, including the regulation of cell proliferation, differentiation, and survival. It is a negative regulator of the PD-L1 signaling pathway, which is involved in the regulation of immune responses and cancer progression.

THSD1 is also known as PD-L1, which is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the superfamily of protein tyrosine kinase (PTK), which is a family of enzymes that regulate protein tyrosine phosphorylation (PT) in response to extracellular signals.

THSD1 is a negative regulator of the PD-L1 signaling pathway, which is involved in the regulation of immune responses and cancer progression. It is a critical protein that helps to maintain the balance of positive and negative regulation in the cell, ensuring the proper functioning of the cell and the proper control of cell growth and differentiation.

In addition to its role in the regulation of cellular signaling pathways, THSD1 is also involved in the regulation of multiple cellular processes, including cell adhesion, migration, and invasion. It is a critical protein that helps to maintain the integrity of the blood-brain barrier, which is responsible for the regulation of the flow of blood and nutrients to the brain and for the removal of waste products.

THSD1 is also involved in the regulation of neurotransmitter release and synaptic plasticity, which is the ability of the brain to change and adapt over time. It is a critical protein that helps to regulate the release of neurotransmitters, such as dopamine and serotonin, which are involved in the regulation of mood, emotion, and cognitive function.

In conclusion, THSD1 is a protein that is involved in the regulation of multiple cellular processes, including cell adhesion, migration, and invasion, as well as the regulation of neurotransmitter release and synaptic plasticity. It is a critical protein that helps to maintain the balance of positive and negative regulation in the cell, ensuring the proper functioning of the cell and the proper control of cell growth and differentiation. THSD1 is a potential drug target and a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Protein Name: Thrombospondin Type 1 Domain Containing 1

Functions: Is a positive regulator of nascent focal adhesion assembly, involved in the modulation of endothelial cell attachment to the extracellular matrix

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