Target Name: TIMM9
NCBI ID: G26520
Other Name(s): translocase of inner mitochondrial membrane 9 | Translocase of inner mitochondrial membrane 9, transcript variant 1 | translocase of inner mitochondrial membrane 9 homolog | TIM9_HUMAN | TIMM9 variant 1 | TIM9 | Mitochondrial import inner membrane translocase subunit Tim9 (isoform a) | TIM9A | Mitochondrial import inner membrane translocase subunit Tim9

TIMM9: A Potential Drug Target and Biomarker for Mitochondrial Dysfunction

Mitochondria are essential organelles that play a crucial role in the cell's energy metabolism. They are the primary powerhouses of the cell, producing the majority of ATP, which is the cell's primary energy currency. Mitochondria also participate in various signaling pathways and are involved in the development and aging process. Damage to mitochondria can lead to a range of diseases, including neurodegenerative disorders, cardiomyopathies, and cancer.

TIMM9, or translocase of inner mitochondrial membrane 9, is a protein that is expressed in high levels in the mitochondria. It plays a crucial role in the structure and function of the mitochondrial membrane and is involved in various cellular processes, including the import of nutrients, the export of waste products, and the regulation of proton fluxes.

Potential Drug Target

TIMM9 has been identified as a potential drug target for several reasons. First, it is expressed in high levels in the mitochondria, which makes it an attractive target for drugs that want to modulate mitochondrial function. Second, TIMM9 is involved in various cellular processes that are crucial for the survival of the cell, making it an attractive target for drugs that want to improve cellular health.

TIMM9 functions as a translocase, which means it can transport molecules across the inner mitochondrial membrane. It plays a crucial role in the import of nutrients, such as oxygen and nutrients, into the mitochondria. It also functions in the export of waste products, such as carbon dioxide and pyruvate, which are crucial for the production of ATP. In addition, TIMM9 is involved in the regulation of proton fluxes, which is crucial for the maintenance of the proton gradient and the production of ATP.

Research has shown that TIMM9 is involved in a variety of cellular processes that are important for the survival of the cell. For example, studies have shown that TIMM9 plays a role in the regulation of mitochondrial fusion, which is the process by which new mitochondria are formed from existing ones. Additionally, TIMM9 is involved in the regulation of mitochondrial fission, which is the process by which one mitochondria divides into two.

Biomarker

TIMM9 has also been identified as a potential biomarker for several reasons. First, its expression is highly upregulated in the mitochondria, which makes it an attractive target for biomarkers that want to monitor cellular processes in the mitochondria. Second, its function is critical for the survival of the cell, which makes it an attractive target for biomarkers that want to monitor cellular processes that are crucial for the survival of the cell.

Studies have shown that TIMM9 is involved in the regulation of cellular processes that are important for the survival of the cell. For example, studies have shown that TIMM9 plays a role in the regulation of apoptosis, which is the process by which cells die and are removed from the body. Additionally, TIMM9 is involved in the regulation of autophagy, which is the process by which cells break down and recycle their own damaged or unnecessary components.

Conclusion

TIMM9 is a protein that is expressed in high levels in the mitochondria and plays a crucial role in the structure and function of the mitochondrial membrane. It is involved in various cellular processes that are important for the survival of the cell, including the regulation of mitochondrial fusion, fission, and apoptosis. As a result, TIMM9 has been identified as a potential drug target and biomarker for several diseases, including neurodegenerative disorders, cardiomyopathies, and cancer. Further research is needed to fully understand the role of TIMM9 in

Protein Name: Translocase Of Inner Mitochondrial Membrane 9

Functions: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space

More Common Targets

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