Target Name: DOLPP1
NCBI ID: G57171
Other Name(s): dolichyl pyrophosphate phosphatase 1 | Linked to Surfeit genes in Fugu rubripes 2 | dolichyldiphosphatase 1 | DOPP1_HUMAN | Dolichyldiphosphatase 1 | linked to Surfeit genes in Fugu rubripes 2 | Dolichyldiphosphatase 1, transcript variant 1 | DOLPP1 variant 1 | LSFR2 | Dolichyldiphosphatase 1 (isoform a) | Dolichyl pyrophosphate phosphatase 1

Targeting DOLPP1: A Potential Drug and Biomarker for Human Health and Disease

Dolichyl pyrophosphate phosphatase 1 (DOLPP1) is a protein that is expressed in various tissues throughout the body, including the brain, muscle, and heart. It is a key enzyme in the metabolic ofoligosperms, which are the basic building blocks of cell membranes. DOLPP1 is involved in the breakdown of these building blocks and is essential for the development and maintenance of cellular structures.

DOLPP1 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of cell proliferation, differentiation, and survival. DOLPP1 has also been shown to be involved in the regulation of inflammation and immune responses.

DOLPP1 is a potential drug target for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its involvement in the regulation of cellular processes that are important for human health and disease makes it an attractive target for drug development.

One of the potential advantages of targeting DOLPP1 is its central role in the regulation of cellular processes that are important for human health and disease. This makes it less likely to have unintended consequences and can result in more effective and targeted treatments. Additionally, DOLPP1 is well-characterized and has a clear function in the cell, which can make it easier to understand and modify its activity.

Another advantage of targeting DOLPP1 is its potential to be used in combination with other treatments. Because DOLPP1 is involved in the regulation of cellular processes that are important for human health and disease, it may be useful in treating conditions that are treated with other therapies. This could result in more effective and personalized treatments.

DOLPP1 is also a good candidate for a biomarker, which can be used to monitor the progression of disease and the effectiveness of treatments. This can be important for identifying potential drug targets and for evaluating the effectiveness of new treatments.

In conclusion, DOLPP1 is a protein that is involved in the regulation of essential cellular processes that are important for human health and disease. Its potential as a drug target and biomarker makes it an attractive target for drug development. Further research is needed to fully understand its role in the regulation of cellular processes and to develop effective treatments.

Protein Name: Dolichyldiphosphatase 1

Functions: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity)

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