Lipase-like AB-Hydrolase Domain Containing 2 (LIPK): Potential Drug Target Or Biomarker
Lipase-like AB-Hydrolase Domain Containing 2 (LIPK): Potential Drug Target Or Biomarker
Lipase-like, ab-hydrolase domain containing 2 (LIPK) is a protein that is expressed in various tissues and cells in the human body. It is a member of the Lipase-like Superfamily 1 and has been identified as a potential drug target or biomarker.
LIPK is a 21-kDa protein that is localized to the endoplasmic reticulum (ER) and is involved in various cellular processes, including metabolism, inflammation, and stress. It is a key regulator of lipid metabolism and has been shown to play a role in the regulation of cellular signaling pathways, such as the TGF-β pathway.
One of the key functions of LIPK is its ability to catalyze the hydrolysis of lipids, which is critical for the production of energy and the maintenance of cellular membrane structure. LIPK is also involved in the regulation of lipid metabolism and has been shown to play a role in the treatment of various metabolic disorders, such as obesity and type 2 diabetes.
In addition to its role in lipid metabolism, LIPK is also involved in the regulation of cellular signaling pathways. It is a key regulator of the TGF-β pathway, which is involved in cell growth, differentiation, and inflammation. LIPK has also been shown to play a role in the regulation of cell proliferation and has been shown to be involved in the development of various types of cancer.
LIPK is also involved in the regulation of cellular stress responses. It has been shown to play a role in the regulation of cellular stress responses, including the production of reactive oxygen species (ROS) and the production of inflammatory cytokines. This may have important implications for the development of diseases that are characterized by cellular stress, such as neurodegenerative diseases and chronic inflammatory diseases.
In conclusion, LIPK is a protein that is expressed in various tissues and cells in the human body and is involved in various cellular processes, including metabolism, inflammation, and stress. It is a key regulator of lipid metabolism and has been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway. LIPK may also be a potential drug target or biomarker for the development of various diseases. Further research is needed to fully understand the role of LIPK in cellular processes and its potential as a drug target or biomarker.
Protein Name: Lipase Family Member K
Functions: Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers
More Common Targets
LIPM | LIPN | Lipoxygenase | Liprin-beta-1-like | LIPT1 | LIPT2 | LIPT2-AS1 | LITAF | Liver Bile Transporters (LBAT) | LIX1 | LIX1-AS1 | LIX1L | LKAAEAR1 | LKB1-LIP1-SMAD4 complex | LL22NC03-63E9.3 | LLCFC1 | LLGL1 | LLGL2 | LLPH | LMAN1 | LMAN1L | LMAN2 | LMAN2L | LMBR1 | LMBR1L | LMBRD1 | LMBRD2 | LMCD1 | LMCD1-AS1 | LMF1 | LMF2 | LMLN | LMNA | LMNB1 | LMNB2 | LMNTD1 | LMNTD2 | LMNTD2-AS1 | LMO1 | LMO2 | LMO3 | LMO4 | LMO7 | LMO7-AS1 | LMO7DN | LMOD1 | LMOD2 | LMOD3 | LMTK2 | LMTK3 | LMX1A | LMX1B | LMX1B-DT | LNC-LBCS | LNCAROD | LNCARSR | LNCATV | LNCNEF | LNCOC1 | LNCOG | LNCPRESS1 | LNCRI | LNCRNA-ATB | LNCRNA-IUR | LNCTAM34A | LNP1 | LNPEP | LNPK | LNX1 | LNX1-AS1 | LNX2 | LOC100127946 | LOC100127955 | LOC100128002 | LOC100128028 | LOC100128050 | LOC100128059 | LOC100128079 | LOC100128093 | LOC100128164 | LOC100128242 | LOC100128288 | LOC100128317 | LOC100128361 | LOC100128398 | LOC100128494 | LOC100128593 | LOC100128770 | LOC100128966 | LOC100128988 | LOC100129034 | LOC100129098 | LOC100129148 | LOC100129175 | LOC100129203 | LOC100129215 | LOC100129316 | LOC100129381 | LOC100129434 | LOC100129455