SNORD77: A Potential Drug Target and Biomarker (G692197)

Target Name: SNORD77

NCBI ID: G692197

Other Name(s): small nucleolar RNA, C/D box 77 | U77 | Small nucleolar RNA, C/D box 77 | SNORD77A

SNORD77: A Potential Drug Target and Biomarker

Small nucleolar RNA (snRNA) is a non-coding RNA molecule that plays a critical role in the regulation of gene expression in eukaryotic cells. One of the most well-known snRNAs is SNORD77, which is located in the C/D box 77 of the 28S rRNA molecule. The function and regulation of SNORD77 are of great interest from a therapeutic perspective due to its involvement in various cellular processes, including cell growth, apoptosis, and translation of RNA molecules.

SNORD77 is a 24.3-kb RNA molecule that contains 21 unique amino acid residues. It is primarily localized to the cytoplasm and is involved in various cellular processes, including DNA replication, transcription, and translation of RNA molecules. SNORD77 has been shown to play a critical role in the regulation of gene expression in various cell types, including cancer cells, stem cells, and epithelial cells.

One of the most significant functions of SNORD77 is its role in the regulation of gene expression. SNORD77 has been shown to interact with various protein molecules, including Ku70 and Snail, which are involved in the regulation of DNA replication and transcription, respectively. These interactions between SNORD77 and Ku70 and Snail have been shown to play a critical role in the regulation of cell growth and apoptosis.

In addition to its role in gene expression, SNORD77 is also involved in the regulation of translation of RNA molecules. SNORD77 has been shown to interact with various protein molecules, including the translation factor IFP-1, which is involved in the regulation of protein synthesis and has been shown to play a critical role in cancer progression.

SNORD77 has also been shown to play a critical role in the regulation of DNA replication. SNORD77 has been shown to interact with the DNA replication protein DNAT2, which is involved in the regulation of DNA replication and has been shown to play a critical role in the development of cancer.

SNORD77 is also involved in the regulation of cell apoptosis. SNORD77 has been shown to interact with various protein molecules, including the apoptosis-associated protein p62, which is involved in the regulation of cell apoptosis and has been shown to play a critical role in the development of cancer.

In conclusion, SNORD77 is a highly conserved non-coding RNA molecule that plays a critical role in various cellular processes, including gene expression, translation, DNA replication, and apoptosis. Its involvement in these processes makes SNORD77 an attractive drug target and biomarker for various diseases, including cancer. Further research is needed to fully understand the role of SNORD77 in cellular processes and its potential as a drug target.

Protein Name: Small Nucleolar RNA, C/D Box 77

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