Target Name: ZNF141
NCBI ID: G7700
Other Name(s): zinc finger protein 141 (clone pHZ-44) | Zinc finger protein 141 | Zinc finger protein 141 (clone pHZ-44) | zinc finger protein 141 | ZNF141 variant 1 | Zinc finger protein 141, transcript variant 1 | ZN141_HUMAN | Zinc finger protein 141 (isoform 1) | D4S90 | pHZ-44 | PHZ-44

ZNF141: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes. ZNF141, also known as zinc finger protein 141 (clone pHZ-44), is a ZFP that is expressed in various tissues and cell types in the human body. It is a 21-kDa protein that contains a unique zinc finger domain, which is responsible for its unique structure and function.

The zinc finger domain is a structural motif that consists of a specific arrangement of amino acids, which is characterized by a conserved pattern of alternating zinc fingers and a characteristic loop region. ZNF141 has four zinc fingers, each of which is involved in the formation of a distinct protein-protein interaction network.

One of the unique features of ZNF141 is its expression pattern. It is primarily expressed in the brain, where it is involved in the development and maintenance of neural circuits. It is also expressed in other tissues, including the heart, kidneys, and liver. This suggests that it may be a potential drug target that can be used to treat a variety of neurological and systemic disorders.

In addition to its expression pattern, ZNF141 has also been shown to play a role in various cellular processes. It is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. It is also involved in the regulation of cell signaling, which is the process by which cells communicate with one another to coordinate their activities.

The zinc finger domain of ZNF141 is known for its ability to interact with other proteins. This interaction is important for the regulation of various cellular processes, including cell signaling and cell adhesion. ZNF141 has been shown to interact with several protein partners, including the transcription factor NF-kappa-B.

The unique structure of ZNF141 and its involvement in various cellular processes make it an attractive drug target. Studies have shown that blocking the activity of ZNF141 using small molecules or antibodies can lead to the inhibition of cellular processes that are involved in the development and maintenance of neural circuits. This suggests that ZNF141 may be a useful biomarker for the diagnosis and treatment of neurological and systemic disorders.

In conclusion, ZNF141 is a unique and highly expressed protein that plays a crucial role in various cellular processes. Its zinc finger domain and its interaction with other proteins make it an attractive drug target. The inhibition of cellular processes by ZNF141 may be a useful biomarker for the diagnosis and treatment of neurological and systemic disorders. Further research is needed to fully understand the role of ZNF141 in cellular processes and its potential as a drug target.

Protein Name: Zinc Finger Protein 141

Functions: May be involved in transcriptional regulation as a repressor. Plays a role in limb development

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