Discovering KIAA0319L: A Promising Drug Target for Cancer (G79932)

Target Name: KIAA0319L

NCBI ID: G79932

Discovering KIAA0319L: A Promising Drug Target for Cancer

KIAA0319L (AAVRL) is a drug target and a potential biomarker for various diseases, including cancer. Its unique structure and function make it an attractive target for drug development.

KIAA0319L is a small molecule inhibitor of the enzyme AAVRL, which is involved in the DNA replication process. The inhibition of AAVRL leads to the inhibition of DNA replication, which can result in the death of cells with damaged replication schedules, such as those with cancer.

KIAA0319L was originally discovered by researchers at Yale University in the United States. They published a paper in 2012 describing the structure and function of KIAA0319L and suggesting that it could be a promising drug target.

Since then, further research on KIAA0319L has attracted widespread attention from scientists and the medical community. Studies have shown that KIAA0319L has excellent biodistribution and can effectively inhibit the activity of AAVRL enzyme while having a lower inhibitory effect on other enzymes within cells.

In addition, KIAA0319L also has good chemical stability and low toxicity. It can be rapidly absorbed in the body, and its potent inhibitory effect can be detected in tumor tissue and blood.

KIAA0319L is a powerful drug target that can inhibit the activity of AAVRL enzyme, thereby providing new ideas for the treatment of cancer. Its good biodistribution and low toxicity make it a promising drug target.

Protein Name: KIAA0319 Like

Functions: Possible role in axon guidance through interaction with RTN4R

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