KIAA1958: A Potential Drug Target and Biomarker (G158405)

Target Name: KIAA1958

NCBI ID: G158405

KIAA1958: A Potential Drug Target and Biomarker

Introduction

KIAA1958 is a unique protein that has been identified as a potential drug target and biomarker. It is a non-coding RNA molecule that is expressed in various tissues and cell types, including brain, heart, and muscle. The function of KIAA1958 is not well understood, but it is known to play a role in the regulation of gene expression and cell signaling.

KIAA1958 is a 20-kDa protein that consists of 195 amino acid residues. It is characterized by a unique fold that includes a conserved N-terminal region, a characteristic 伪-helices region, and a C-terminal region that is rich in conserved amino acids sequence. The protein is expressed in various tissues and cell types, including brain, heart, and muscle, and is associated with various cellular processes, including cell signaling, cell adhesion, and neurodegeneration.

Potential Drug Target

The potential drug target for KIAA1958 is its role in cell signaling. KIAA1958 has been shown to play a role in the regulation of neural cell proliferation, differentiation, and survival. It is also involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

In addition, KIAA1958 has been shown to play a role in the regulation of inflammation and immune response. It is involved in the regulation of the immune response, cell recruitment, and the production of inflammatory cytokines.

BIOMARKER

KIAA1958 has also been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In cancer, KIAA1958 has been shown to be involved in the regulation of cell proliferation, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels). It is also involved in the regulation of cell signaling, including the regulation of the TGF-β pathway.

In neurodegenerative diseases, KIAA1958 has been shown to play a role in the regulation of neurotransmitter synthesis and release, as well as the regulation of neuronal excitability. It is also involved in the regulation of cell signaling, including the regulation of the NMDA receptor.

In cardiovascular diseases, KIAA1958 has been shown to play a role in the regulation of cell signaling, including the regulation of the phosphatidylinositol (PIM) signaling pathway. It is also involved in the regulation of cell adhesion, as well as the production of pro-inflammatory cytokines.

Conclusion

In conclusion, KIAA1958 is a unique protein that has the potential to be a drug target and biomarker. Its unique fold and various functions in various tissues and cell types make it an attractive target for drug development. Further research is needed to fully understand the functions of KIAA1958 and its potential as a drug and biomarker.

Protein Name: KIAA1958

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