KIF11: A Potential Drug Target Or Biomarker (G3832)

Target Name: KIF11

NCBI ID: G3832

KIF11: A Potential Drug Target Or Biomarker

KIF11 (Kirsten Foundation Promises 11) is a protein that is expressed in various tissues of the human body, including the brain, pancreas, and heart. Its primary function is to help regulate the movement of ions and molecules across cell membranes, which is essential for maintaining proper signaling and physiological processes.

Recent studies have suggested that KIF11 may have potential as a drug target or biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases.

One of the key reasons for the interest in KIF11 is its role in the regulation of ion channels, which are critical for the flow of electrical signals in cells. Many diseases are caused by the misregulation of ion channels, which can lead to the buildup of harmful substances or the disruption of proper signaling pathways.

For example, in cancer, the misregulation of ion channels can contribute to the development and progression of the disease. Researchers have found that KIF11 is often expressed in various types of cancer, and that its levels are correlated with the severity of the disease.

Another potential application of KIF11 is its role as a biomarker for neurodegenerative disorders. Many of these disorders, such as Alzheimer's disease and Parkinson's disease, are characterized by the buildup of harmful substances in the brain and the disruption of proper signaling pathways. KIF11 has been shown to be involved in the regulation of ion channels in these disorders, which may make it a useful diagnostic or therapeutic target.

In addition to its potential as a drug target or biomarker, KIF11 has also been shown to have potential as a therapeutic agent for a variety of conditions. For example, studies have found that KIF11 can be expressed in the brains of individuals with Alzheimer's disease, and that its levels are associated with the severity of the disease.

Furthermore, KIF11 has also been shown to be involved in the regulation of stem cell proliferation and the development of tissues. This suggests that it may have potential as a therapeutic agent for a variety of conditions, including cancer.

Overall, KIF11 is a protein that has potential as a drug target or biomarker for a variety of diseases. Further research is needed to fully understand its role and potential applications in medicine.

Protein Name: Kinesin Family Member 11

Functions: Motor protein required for establishing a bipolar spindle during mitosis (PubMed:19001501). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769)

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