Discovering The Potential Drug Target KIAA1586 (G57691)
Discovering The Potential Drug Target KIAA1586
KiAA1586 is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and pancreas. It is a member of the Kallikrein-related protein family and is involved in the regulation of various cellular processes in the body . Despite its importance, little is known about KiAA1586, and it has not been extensively studied. In this article, we will explore KiAA1586 as a potential drug target and its potential implications for various diseases.
KIAA1586 Structure and Function
KIAA1586 is a 21-kDa protein that is expressed in various tissues of the human body. It is characterized by a single transmembrane domain and a single intracellular tail. The protein has a calculated molecular mass of 19.9 kDa and a calculated pI of 9.98. KIAA1586 is involved in various cellular processes, including cell signaling, cell adhesion, and cell survival.
One of the most significant functions of KIAA1586 is its role in cell signaling. The protein is involved in the regulation of several signaling pathways, including the TGF-β pathway and the Wnt pathway. TGF-β is a well-known signaling pathway that is involved in the regulation of cell growth, differentiation, and survival. The TGF-β pathway is a critical pathway that is involved in the development and maintenance of tissues in the body. KIAA1586 is known to be involved in the regulation of TGF-β signaling by activating the negative signaling pathway.
Another function of KIAA1586 is its role in cell adhesion. The protein is involved in the regulation of cell-cell adhesion, which is an important process that is involved in the development and maintenance of tissues in the body. KIAA1586 is known to be involved in the regulation of cell-cell adhesion by activating the negative signaling pathway.
KIAA1586 is also involved in the regulation of cell survival. The protein is known to be involved in the regulation of cell survival by activating the positive signaling pathway. This pathway is involved in the regulation of cell growth and apoptosis, which are important processes that are involved in the development and maintenance of tissues in the body.
KIAA1586 Interactions with Other Proteins
KIAA1586 is a protein that is involved in several interactions with other proteins in the body. One of the most significant interactions of KIAA1586 is with the protein known as PDGFR-尾. PDGFR-尾 is a protein that is involved in cell signaling, specifically in the regulation of cell growth and differentiation. KIAA1586 is known to interact with PDGFR-尾 by activating its negative signaling pathway.
KIAA1586 is also known to interact with several other proteins, including TGF-伪, NF-kappa-B, and NF-cyclic nucleotide-binding protein (NF-p). These proteins are involved in various cellular processes in the body, including cell signaling , cell adhesion, and cell survival.
KIAA1586 as a Drug Target
KIAA1586 is a protein that is involved in several cellular processes in the body, including cell signaling, cell adhesion, and cell survival. As a result, KIAA1586 is a potential drug target. Several studies have suggested that inhibiting KIAA1586 may be an effective way to treat various diseases.
One of the potential benefits of targeting KIAA1586 is its potential to treat cancer. Cancer is a disease that is characterized by the uncontrolled growth and spread of cells. KIAA1586 is involved in the regulation of cell signaling, and it is possible that inhibiting its activity may be an effective way to treat cancer. Several studies have suggested that inhibiting KIAA1586
Protein Name: KIAA1586
Functions: E3 SUMO-protein ligase; facilitates UBE2I/UBC9-mediated SUMO2 modification of target proteins (PubMed:26524493)
More Common Targets
KIAA1614 | KIAA1656 | KIAA1671 | KIAA1671-AS1 | KIAA1755 | KIAA1958 | KIAA2012 | KIAA2013 | KIAA2026 | KICS2 | KIDINS220 | KIF11 | KIF12 | KIF13A | KIF13B | KIF14 | KIF15 | KIF16B | KIF17 | KIF18A | KIF18B | KIF19 | KIF1A | KIF1B | KIF1C | KIF20A | KIF20B | KIF21A | KIF21B | KIF22 | KIF23 | KIF23-AS1 | KIF24 | KIF25 | KIF25-AS1 | KIF26A | KIF26B | KIF27 | KIF28P | KIF2A | KIF2B | KIF2C | KIF3A | KIF3B | KIF3C | KIF4A | KIF4B | KIF5A | KIF5B | KIF5C | KIF6 | KIF7 | KIF9 | KIF9-AS1 | KIFAP3 | KIFBP | KIFC1 | KIFC2 | KIFC3 | Killer Cell Immunoglobulin-Like Receptor (KIR) | Killer cell immunoglobulin-like receptor 2DS1, transcript variant X1 | KIN | Kinesin-like protein KIF16B (isoform 1) | KIR2DL1 | KIR2DL2 | KIR2DL3 | KIR2DL4 | KIR2DL5A | KIR2DL5B | KIR2DP1 | KIR2DS1 | KIR2DS2 | KIR2DS3 | KIR2DS4 | KIR2DS5 | KIR3DL1 | KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1