Target Name: NUDT22
NCBI ID: G84304
Other Name(s): nudix hydrolase 22 | Nudix motif 22 | nucleoside diphosphate-linked moiety X motif 22 | nudix motif 22 | UGPPase | Nudix (nucleoside diphosphate linked moiety X)-type motif 22, transcript variant 1 | NUDT22 variant 1 | nudix (nucleoside diphosphate linked moiety X)-type motif 22 | Uridine diphosphate glucose pyrophosphatase NUDT22 | NUD22_HUMAN | UDPG pyrophosphatase | Nucleoside diphosphate-linked moiety X motif 22 (isoform a)

NUDT22: A Potential Drug Target and Biomarker

Nudix hydrolase 22 (NUDT22) is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and liver. It is a member of the NUDT family of enzymes, which are involved in the breakdown of neurotransmitters, such as dopamine, serotonin, and GABA. NUDT22 is expressed in high levels in the brain and has been implicated in the development and progression of various neurological disorders, including depression, anxiety, and schizophrenia.

Recent studies have suggested that NUDT22 may have potential as a drug target and biomarker. One reason for this is that NUDT22 has been shown to play a role in the production of reactive oxygen species (ROS), which can damage cellular components and contribute to the development of oxidative stress-induced diseases. NUDT22 has also been shown to interact with various neurotransmitters, including dopamine, serotonin, and GABA, and has been shown to modulate their levels in the brain.

In addition, NUDT22 has been shown to be involved in the production of various signaling molecules, including neurotrophins and chemokines. These molecules are involved in the regulation of neural circuits and have been implicated in the development and progression of various neurological disorders.

Despite these potential drug-relevant properties, little is known about the biology of NUDT22. Therefore, the potential utility of NUDT22 as a drug target or biomarker remains to be determined. Further research is needed to understand the role of NUDT22 in the development and progression of neurological disorders and to explore its potential as a drug target or biomarker.

In conclusion, NUDT22 is a protein that has been shown to play a role in the breakdown of neurotransmitters and the production of reactive oxygen species. Its potential as a drug target and biomarker is due to its involvement in the regulation of neural circuits and the production of signaling molecules. Further research is needed to fully understand its role in the development and progression of neurological disorders.

Protein Name: Nudix Hydrolase 22

Functions: Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and UDP-galactose to galactose 1-phosphate and UMP. Preferred substrate is UDP-glucose

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NUDT3 | NUDT4 | NUDT4B | NUDT4P2 | NUDT5 | NUDT6 | NUDT7 | NUDT8 | NUDT9 | NUDT9P1 | NUF2 | NUFIP1 | NUFIP2 | NUGGC | NUMA1 | NUMB | NUMBL | NUP107 | Nup107-160 complex | NUP133 | NUP153 | NUP155 | NUP160 | NUP188 | NUP205 | NUP210 | NUP210L | NUP210P1 | NUP210P2 | NUP214 | NUP35 | NUP37 | NUP42 | NUP43 | NUP50 | NUP50-DT | NUP54 | NUP58 | NUP62 | NUP62CL | NUP85 | NUP88 | NUP93 | NUP98 | NUPR1 | NUPR2 | NUS1 | NUS1P1 | NUS1P3 | NUSAP1 | NUTF2 | NUTF2P4 | NUTM1 | NUTM2A | NUTM2A-AS1 | NUTM2B | NUTM2B-AS1 | NUTM2D | NUTM2E | NUTM2F | NUTM2G | NVL | NWD1 | NWD2 | NXF1 | NXF2 | NXF3 | NXF4 | NXF5 | NXN | NXNL1 | NXNL2 | NXPE1 | NXPE2 | NXPE3 | NXPE4 | NXPH1 | NXPH2 | NXPH3 | NXPH4 | NXT1 | NXT2 | NXTAR | NYAP1 | NYAP2 | NYNRIN | NYX | OACYLP | OAF | OARD1 | OAS1 | OAS2 | OAS3 | OASL | OAT | OATP1 | OAZ1 | OAZ2 | OAZ3 | OBI1