TNFRSF25: Key Regulator of Inflammation and Tissue Repair (G8718)

Target Name: TNFRSF25

NCBI ID: G8718

TNFRSF25: Key Regulator of Inflammation and Tissue Repair

TNFRSF25 (TNF-receptor superfamily 25) is a protein that is expressed in various tissues throughout the body, including the nervous system, endothelial cells, and various immune cells. It is a key regulator of inflammation and immune responses, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of TNFRSF25 is its role as a Death Receptor, which is a protein that is involved in the process of cell death. When TNFRSF25 is activated, it can induce the production of pro-inflammatory cytokines, such as TNF-alpha, which can contribute to inflammation and tissue damage.

In addition to its role in cell death, TNFRSF25 is also involved in a number of other cellular processes that are important for tissue repair and regeneration. For example, it has been shown to play a key role in the regulation of stem cell proliferation and differentiation, and has been implicated in the development of various diseases, including cancer.

Given its involvement in a number of important cellular processes, TNFRSF25 has been considered as a potential drug target or biomarker for a variety of diseases. For example, there is evidence to suggest that inhibiting the activity of TNFRSF25 may have therapeutic benefits for a number of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease.

In addition to its potential therapeutic applications, TNFRSF25 is also an attractive biomarker for a variety of diseases. For example, it has been shown to be a reliable indicator of disease severity in various neurodegenerative diseases, and has been used as a diagnostic marker in a number of studies.

Overall, TNFRSF25 is a protein that has important roles in a number of cellular processes that are important for tissue repair and regeneration. Its potential as a drug target or biomarker for a variety of diseases makes it an important area of research for scientists and clinicians. Further studies are needed to fully understand its functions and potential therapeutic applications.

Protein Name: TNF Receptor Superfamily Member 25

Functions: Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis

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