Double Homeobox Protein 4: Potential Drug Target and Biomarker

Target Name: Double homeobox protein 4

NCBI ID: P16499

Other Name(s): DUX4 | Double homeobox protein 4/10 | Double homeobox protein 10 | Double homeobox protein DUX10

Double Homeobox Protein 4: Potential Drug Target and Biomarker

Double homeobox protein 4 (DUX4) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and pancreas. Its function is not well understood, but it is known to play a role in the development and maintenance of tissues, including the nervous system and blood vessels.

DUX4 is a member of the homeobox gene family, which is a group of genes that encode for proteins involved in the development and organization of tissues. The homeobox genes have been implicated in the development of a variety of human diseases, including cancer, neurodegenerative diseases, and developmental disorders.

DUX4 is expressed in many different tissues and organs, including the brain, heart, liver, and pancreas. It is highly expressed in the brain, where it is found in the postsynaptic terminal density of dendrites in neurons and in the cell body of neurons. It is also found in the heart, where it is involved in the development and maintenance of heart muscle.

In addition to its expression in neural and cardiovascular tissues, DUX4 is also expressed in other organs and tissues, including the liver and pancreas. It is highly expressed in the liver, where it is involved in the development and maintenance of liver cells. It is also found in the pancreas, where it is involved in the development and maintenance of pancreatic ducts, which carry digestive enzymes from the pancreas to the small intestine.

While the exact function of DUX4 is not well understood, it is thought to play a role in the development and maintenance of tissues, including neural and cardiovascular tissues. It is possible that DUX4 promotes the formation and maintenance of these tissues, or that it is involved in the regulation of their growth and differentiation.

DUX4 is also a potential drug target and biomarker. Its expression in various tissues and organs makes it a promising target for the development of new therapies for a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

In conclusion, DUX4 is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and pancreas. While its exact function is not well understood, it is thought to play a role in the development and maintenance of tissues, including neural and cardiovascular tissues. Its expression in various tissues also makes it a potential drug target and biomarker for the development of new therapies for a variety of diseases. Further research is needed to fully understand its role and function in the body.

Protein Name: Double Homeobox Protein 4

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